TEX11 and MAPK9

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TEX11	MAPK9
Description		testis expressed 11	mitogen-activated protein kinase 9
Image		No pdb structure
GO Annotations	Cellular Component	Synaptonemal Complex Central Element	Nucleus Nucleoplasm Cytoplasm Mitochondrion Cytosol
	Molecular Function	Protein Binding	JUN Kinase Activity MAP Kinase Activity Protein Serine/threonine/tyrosine Kinase Activity Protein Binding ATP Binding Transcription Factor Binding
	Biological Process	Resolution Of Meiotic Recombination Intermediates Meiotic Gene Conversion Male Meiosis Chromosome Segregation Synaptonemal Complex Assembly Reciprocal Meiotic Recombination Male Gonad Development Fertilization Negative Regulation Of Apoptotic Process Chiasma Assembly	Protein Phosphorylation JNK Cascade JUN Phosphorylation Regulation Of Gene Expression Positive Regulation Of Gene Expression Positive Regulation Of Macrophage Derived Foam Cell Differentiation Peptidyl-serine Phosphorylation Positive Regulation Of Protein Ubiquitination Cellular Response To Reactive Oxygen Species Intracellular Signal Transduction Fc-epsilon Receptor Signaling Pathway Regulation Of Circadian Rhythm Rhythmic Process Regulation Of DNA-binding Transcription Factor Activity Protein Localization To Tricellular Tight Junction Cellular Response To Cadmium Ion Positive Regulation Of Podosome Assembly Positive Regulation Of Transcription Factor Catabolic Process Positive Regulation Of Apoptotic Signaling Pathway
Pathways			Oxidative Stress Induced Senescence FCERI mediated MAPK activation JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 Activation of the AP-1 family of transcription factors
Drugs			N-{3-[5-(1H-1,2,4-triazol-3-yl)-1H-indazol-3-yl]phenyl}furan-2-carboxamide
Diseases
GWAS		Mean corpuscular volume ( 29403010) Waist circumference ( 28552196)	Blood protein levels ( 30072576)
Interacting Genes		71 interacting genes: ATXN3 BCL2L2 BEX1 BORCS8 BORCS8-MEF2B C10orf82 C2CD6 C6orf226 CBY2 CCDC198 CCND2 CCND3 CDKN1A CDKN2D CENPP CEP55 CFAP53 CLK1 CNOT7 COL20A1 CXCL14 DUSP21 DUSP6 EFHC1 EXOSC1 EXOSC5 FAM156A FBF1 GATAD2B HYI ING3 KIAA0408 KIAA1217 LIN37 LSM2 MAD1L1 MAPK9 MAPKBP1 MORF4L1 MRFAP1 MRFAP1L1 MTA1 MYEF2 NECAB2 NEFL NRIP1 PDZD11 PIAS1 POM121 PPP1R18 QKI REXO1L6P RIBC1 RIBC2 SEPTIN1 SH3GLB2 SHOC1 SNW1 SNX32 SNX7 STMN2 SUPT5H TBC1D22B TCHP TIPIN TOPBP1 TSC22D4 TSG101 UTP14C VIL1 ZNF414	77 interacting genes: ACP5 AKT1 ARRB1 ARRB2 ATF2 ATF7 BCL2L1 BCL2L11 C1orf94 CASP3 CCDC33 CDC25B CDC25C CEP126 CEP44 CLU CTBP1 CTNNB1 CYHR1 DUSP16 DUSP19 DUSP4 EEF2K EFHC2 EGFR ELK1 ELK3 FBXO7 GRB2 H3-3A HDAC9 HSF1 IRS1 JDP2 JUN JUNB JUND L3MBTL3 LMAN2 LNX1 LNX2 MACF1 MAP2K4 MAP2K7 MAP3K1 MAP3K10 MAPK8IP1 MAPK8IP2 MAPK8IP3 MAPKAPK5 MAPKBP1 MAPT MEOX1 NCF1 NCSTN NFATC3 NFATC4 PRKD1 PSEN1 RB1 RPS6KB1 SF3B4 SH3BP5 SHMT1 SMAD2 SMAD3 SMCO3 SSU72 TEX11 TOB1 TP53 TRAF2 TUSC2 WDR62 XPNPEP1 XPO7 ZBTB25
Entrez ID		56159	5601
HPRD ID		02256	04206
Ensembl ID		ENSG00000120498	ENSG00000050748
Uniprot IDs		Q8IYF3	D7R525 D7R526 P45984
PDB IDs			3E7O 3NPC
Enriched GO Terms of Interacting Partners?
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