TEX11 and EXOSC1

Number of citations of the paper that reports this interaction (PubMedID 30217970)
1

Data Source:
BioGRID (two hybrid)

		TEX11	EXOSC1
Description		testis expressed 11	exosome component 1
Image		No pdb structure
GO Annotations	Cellular Component	Synaptonemal Complex Central Element	Nuclear Exosome (RNase Complex) Exosome (RNase Complex) Nucleoplasm Nucleolus Cytoplasm Cytosol
	Molecular Function	Protein Binding	RNA Binding Exoribonuclease Activity Protein Binding
	Biological Process	Resolution Of Meiotic Recombination Intermediates Meiotic Gene Conversion Male Meiosis Chromosome Segregation Synaptonemal Complex Assembly Reciprocal Meiotic Recombination Male Gonad Development Fertilization Negative Regulation Of Apoptotic Process Chiasma Assembly	RRNA Processing Regulation Of MRNA Stability Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay RNA Phosphodiester Bond Hydrolysis, Exonucleolytic
Pathways			ATF4 activates genes in response to endoplasmic reticulum stress mRNA decay by 3' to 5' exoribonuclease Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA KSRP (KHSRP) binds and destabilizes mRNA Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		Mean corpuscular volume ( 29403010) Waist circumference ( 28552196)	Blood protein levels ( 30072576) Early spontaneous preterm birth ( 31194736) Spontaneous preterm birth with premature rupture of membranes ( 31194736)
Interacting Genes		71 interacting genes: ATXN3 BCL2L2 BEX1 BORCS8 BORCS8-MEF2B C10orf82 C2CD6 C6orf226 CBY2 CCDC198 CCND2 CCND3 CDKN1A CDKN2D CENPP CEP55 CFAP53 CLK1 CNOT7 COL20A1 CXCL14 DUSP21 DUSP6 EFHC1 EXOSC1 EXOSC5 FAM156A FBF1 GATAD2B HYI ING3 KIAA0408 KIAA1217 LIN37 LSM2 MAD1L1 MAPK9 MAPKBP1 MORF4L1 MRFAP1 MRFAP1L1 MTA1 MYEF2 NECAB2 NEFL NRIP1 PDZD11 PIAS1 POM121 PPP1R18 QKI REXO1L6P RIBC1 RIBC2 SEPTIN1 SH3GLB2 SHOC1 SNW1 SNX32 SNX7 STMN2 SUPT5H TBC1D22B TCHP TIPIN TOPBP1 TSC22D4 TSG101 UTP14C VIL1 ZNF414	27 interacting genes: A2M APP CDC37 DMRTB1 ECSIT EXOC6 EXOSC4 EXOSC5 EXOSC6 EXOSC7 EXOSC9 FHL3 KCTD1 LSM3 MAST1 MPHOSPH6 NOS3 NUP160 PAK5 RBPMS REL RNF32 SH3GLB2 TCF4 TEX11 UPF2 XRN1
Entrez ID		56159	51013
HPRD ID		02256	16223
Ensembl ID		ENSG00000120498	ENSG00000171311
Uniprot IDs		Q8IYF3	B1AMU3 Q9Y3B2
PDB IDs			2NN6 6D6Q 6D6R 6H25
Enriched GO Terms of Interacting Partners?
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