TEX11 and DUSP6

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
HPRD (two hybrid)

		TEX11	DUSP6
Description		testis expressed 11	dual specificity phosphatase 6
Image		No pdb structure
GO Annotations	Cellular Component	Synaptonemal Complex Central Element	Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Protein Binding	Protein Tyrosine Phosphatase Activity Protein Tyrosine/serine/threonine Phosphatase Activity MAP Kinase Tyrosine/serine/threonine Phosphatase Activity
	Biological Process	Resolution Of Meiotic Recombination Intermediates Meiotic Gene Conversion Male Meiosis Chromosome Segregation Synaptonemal Complex Assembly Reciprocal Meiotic Recombination Male Gonad Development Fertilization Negative Regulation Of Apoptotic Process Chiasma Assembly	MAPK Cascade Activation Of MAPK Activity Inactivation Of MAPK Activity Protein Dephosphorylation Response To Organic Cyclic Compound Cell Differentiation Peptidyl-tyrosine Dephosphorylation Response To Drug Positive Regulation Of Apoptotic Process Response To Nitrosative Stress Regulation Of Heart Growth Negative Regulation Of ERK1 And ERK2 Cascade Response To Growth Factor
Pathways			RAF-independent MAPK1/3 activation ERKs are inactivated Negative regulation of MAPK pathway
Drugs
Diseases
GWAS		Mean corpuscular volume ( 29403010) Waist circumference ( 28552196)	Attention deficit hyperactivity disorder ( 29325848 30478444) Night sleep phenotypes ( 27126917)
Interacting Genes		71 interacting genes: ATXN3 BCL2L2 BEX1 BORCS8 BORCS8-MEF2B C10orf82 C2CD6 C6orf226 CBY2 CCDC198 CCND2 CCND3 CDKN1A CDKN2D CENPP CEP55 CFAP53 CLK1 CNOT7 COL20A1 CXCL14 DUSP21 DUSP6 EFHC1 EXOSC1 EXOSC5 FAM156A FBF1 GATAD2B HYI ING3 KIAA0408 KIAA1217 LIN37 LSM2 MAD1L1 MAPK9 MAPKBP1 MORF4L1 MRFAP1 MRFAP1L1 MTA1 MYEF2 NECAB2 NEFL NRIP1 PDZD11 PIAS1 POM121 PPP1R18 QKI REXO1L6P RIBC1 RIBC2 SEPTIN1 SH3GLB2 SHOC1 SNW1 SNX32 SNX7 STMN2 SUPT5H TBC1D22B TCHP TIPIN TOPBP1 TSC22D4 TSG101 UTP14C VIL1 ZNF414	12 interacting genes: AATK ERBB4 GLA LMTK2 LTK MAPK1 MAPK3 MDFI ROR2 SRPK1 TEX11 ZNF212
Entrez ID		56159	1848
HPRD ID		02256	04124
Ensembl ID		ENSG00000120498	ENSG00000139318
Uniprot IDs		Q8IYF3	A0A024RBC1 Q16828 Q53GP9
PDB IDs			1HZM 1MKP
Enriched GO Terms of Interacting Partners?
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