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SLC22A11 and SLC9A3R1
Number of citations of the paper that reports this interaction (PubMedID
16236806
)
24
Data Source:
HPRD
(in vitro, in vivo, two hybrid)
SLC22A11
SLC9A3R1
Description
solute carrier family 22 member 11
SLC9A3 regulator 1
Image
No pdb structure
GO Annotations
Cellular Component
Plasma Membrane
Integral Component Of Plasma Membrane
External Side Of Plasma Membrane
Apical Plasma Membrane
Extracellular Exosome
Ruffle
Cell
Nucleus
Cytoplasm
Microvillus
Endomembrane System
Actin Cytoskeleton
Membrane
Apical Plasma Membrane
Filopodium
Brush Border Membrane
Microvillus Membrane
Vesicle
Stereocilium Tip
Membrane Raft
Perinuclear Region Of Cytoplasm
Extracellular Exosome
Cell Periphery
Sperm Midpiece
Molecular Function
Inorganic Anion Exchanger Activity
Protein Binding
Organic Anion Transmembrane Transporter Activity
Sodium-independent Organic Anion Transmembrane Transporter Activity
Signaling Receptor Binding
Protein Binding
Beta-catenin Binding
Chloride Channel Regulator Activity
Phosphatase Binding
PDZ Domain Binding
Beta-2 Adrenergic Receptor Binding
Protein Self-association
Protein-containing Complex Binding
Myosin II Binding
Protein N-terminus Binding
Dopamine Receptor Binding
Molecular Adaptor Activity
Growth Factor Receptor Binding
Biological Process
Inorganic Anion Transport
Organic Anion Transport
Urate Metabolic Process
Transmembrane Transport
Renal Sodium Ion Transport
Nuclear Migration
Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway
Sensory Perception Of Sound
Negative Regulation Of Cell Proliferation
Regulation Of Cell Shape
Regulation Of Cell Size
Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway
Negative Regulation Of Phosphatidylinositol 3-kinase Signaling
Wnt Signaling Pathway
Gland Morphogenesis
Microvillus Assembly
Actin Cytoskeleton Organization
Negative Regulation Of Cell Migration
Cellular Phosphate Ion Homeostasis
Regulation Of Sodium:proton Antiporter Activity
Negative Regulation Of Sodium:proton Antiporter Activity
Bile Acid Secretion
Glutathione Transport
Positive Regulation Of Ion Transmembrane Transport
Regulation Of Excretion
Establishment Of Epithelial Cell Apical/basal Polarity
Regulation Of Protein Kinase Activity
Negative Regulation Of Mitotic Cell Cycle
Establishment Of Golgi Localization
Negative Regulation Of Protein Kinase B Signaling
Auditory Receptor Cell Stereocilium Organization
Phospholipase C-activating Dopamine Receptor Signaling Pathway
Protein-containing Complex Assembly
Renal Absorption
Negative Regulation Of ERK1 And ERK2 Cascade
Protein Localization To Plasma Membrane
Negative Regulation Of Canonical Wnt Signaling Pathway
Renal Phosphate Ion Absorption
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways
Organic anion transport
Drugs
Cefotaxime
Probenecid
Ceftriaxone
Lesinurad
Diseases
Nephrolithiasis/osteoporosis, hypophosphatemic
GWAS
Obesity-related traits (
23251661
)
Serum uric acid levels (
30993211
26902266
)
Systemic lupus erythematosus (
28714469
)
Urate levels (
20884846
31578528
23263486
)
Urate levels in lean individuals (
25811787
)
Urate levels in overweight individuals (
25811787
)
Uric acid levels (
19503597
)
Dental caries (decayed and filled deciduous teeth) (
31533690
)
Dental caries (decayed and filled deciduous tooth surfaces) (
31533690
)
Fibrinogen (
20031577
)
Monocyte count (
27863252
)
Monocyte percentage of white cells (
27863252
)
Interacting Genes
3 interacting genes:
CAV3
PDZK1
SLC9A3R1
64 interacting genes:
ABCC2
ABCC4
ADRB2
AKAP10
AKT1
ATP6V1B1
ATP6V1E1
AXIN2
BCL10
BCL2A1
CABP1
CD300A
CFTR
CLCN3
CNGA2
COG1
CTNNB1
EGFR
EZR
GC
GFI1
GNA11
GNAQ
GRK6
KCNJ1
LHCGR
LPAR2
MSN
NF2
NOS2
OPRK1
P2RY1
PAG1
PDGFRA
PDGFRB
PDZK1
PHLPP1
PLCB1
PLCB2
PRKCA
PTEN
PTH1R
RDX
RLBP1
SCN4A
SKP2
SLC22A11
SLC22A4
SLC22A5
SLC22A9
SLC26A3
SLC34A1
SLC4A7
SLC4A8
SLC9A3
SLCO1A2
SLCO3A1
ST6GALNAC2
TBC1D10A
TRPC4
TRPC5
YAP1
YES1
ZNF468
Entrez ID
55867
9368
HPRD ID
06161
05406
Ensembl ID
ENSG00000168065
ENSG00000109062
Uniprot IDs
Q9NSA0
O14745
PDB IDs
1G9O
1GQ4
1GQ5
1I92
1SGH
2D10
2JXO
2KJD
2KRG
2M0T
2M0U
2M0V
2OZF
4JL7
4LMM
4MPA
4N6X
4PQW
4Q3H
Enriched GO Terms of Interacting Partners
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