SLC22A11 and PDZK1

Number of citations of the paper that reports this interaction (PubMedID 16236806)
24

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		SLC22A11	PDZK1
Description		solute carrier family 22 member 11	PDZ domain containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Apical Plasma Membrane Extracellular Exosome	Plasma Membrane Brush Border Apical Plasma Membrane Brush Border Membrane Microvillus Membrane Membrane Raft Extracellular Exosome
	Molecular Function	Inorganic Anion Exchanger Activity Protein Binding Organic Anion Transmembrane Transporter Activity Sodium-independent Organic Anion Transmembrane Transporter Activity	Scavenger Receptor Binding Protein Binding PDZ Domain Binding Protein-containing Complex Binding
	Biological Process	Inorganic Anion Transport Organic Anion Transport Urate Metabolic Process Transmembrane Transport	Carnitine Transport Positive Regulation Of Ion Transmembrane Transporter Activity Regulation Of Anion Transport Positive Regulation Of Protein Targeting To Membrane Positive Regulation Of Cation Transmembrane Transport Positive Regulation Of Protein Localization To Membrane Drug Transmembrane Export
Pathways		Organic anion transport
Drugs		Cefotaxime Probenecid Ceftriaxone Lesinurad
Diseases
GWAS		Obesity-related traits ( 23251661) Serum uric acid levels ( 30993211 26902266) Systemic lupus erythematosus ( 28714469) Urate levels ( 20884846 31578528 23263486) Urate levels in lean individuals ( 25811787) Urate levels in overweight individuals ( 25811787) Uric acid levels ( 19503597)	Contrast sensitivity ( 24152035) Serum uric acid levels ( 30993211) Urate levels ( 20884846 31578528 23263486) Urate levels in overweight individuals ( 25811787) Uric acid levels ( 19503597)
Interacting Genes		3 interacting genes: CAV3 PDZK1 SLC9A3R1	29 interacting genes: ABCA1 ABCC2 ABCC4 AKAP10 APP CFTR CLCN3 CRHR1 FARP2 GFAP PDZK1IP1 PEX5 RPS6KA1 SCARB1 SLC15A2 SLC17A1 SLC22A11 SLC22A12 SLC22A4 SLC22A5 SLC26A6 SLC34A1 SLC9A3 SLC9A3R1 SLC9A3R2 SLCO1A2 SLK SSTR5 UBE2I
Entrez ID		55867	5174
HPRD ID		06161	04829
Ensembl ID		ENSG00000168065	ENSG00000174827
Uniprot IDs		Q9NSA0	Q5T2W1
PDB IDs			2EEI 2EEJ 2VSP 3TMH 4Q2P 6EZI
Enriched GO Terms of Interacting Partners?
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