ENAH and ZYX

Number of citations of the paper that reports this interaction (PubMedID 10801818)
46

Data Source:
HPRD (in vivo, in vitro)

		ENAH	ZYX
Description		ENAH actin regulator	zyxin
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Cytoskeleton Plasma Membrane Focal Adhesion Lamellipodium Cell Junction Filopodium Synapse	Stress Fiber Nucleus Cytoplasm Cytosol Adherens Junction Focal Adhesion Phagocytic Vesicle
	Molecular Function	Actin Binding Protein Binding Profilin Binding SH3 Domain Binding WW Domain Binding	RNA Binding Protein Binding Metal Ion Binding
	Biological Process	Axon Guidance Actin Polymerization Or Depolymerization Actin Polymerization-dependent Cell Motility	Cell-matrix Adhesion Signal Transduction Transforming Growth Factor Beta Receptor Signaling Pathway Integrin-mediated Signaling Pathway Cell-cell Signaling Viral Process Stress Fiber Assembly Regulation Of Inflammatory Response Cellular Response To Interferon-gamma
Pathways		Generation of second messenger molecules Signaling by ROBO receptors Signaling by ROBO receptors
Drugs			Artenimol
Diseases
GWAS		Delirium ( 29631748) Depression in smokers ( 30219690) Neuroticism ( 27067015) Obesity-related traits ( 23251661)	Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Blood protein levels ( 28240269) White blood cell count (basophil) ( 27863252)
Interacting Genes		26 interacting genes: ABI1 ABI2 ABI3 ABL1 APBB1 BAIAP2 DNMBP EVL FAT1 FYB1 GPHN HMGB1 MAPK1 PFN1 PRPF40A RAC1 RAD51 ROBO4 SPTA1 TERF2IP TES VASP WAS XIRP1 YAP1 ZYX	30 interacting genes: ACTN1 ATXN1 BSPRY ENAH HIPK3 IMP3 LASP1 LATS1 LIN7A NEBL NEDD9 NME5 OPRM1 PDLIM5 PHF21A RABEPK RGS2 RPH3AL RTN4IP1 SIAH1 SREBF2 TES TUFT1 VASP VAV1 VAV3 WNK1 YPEL3 ZHX1 ZNF384
Entrez ID		55740	7791
HPRD ID		12360	03592
Ensembl ID		ENSG00000154380	ENSG00000159840
Uniprot IDs		A0A4D6J698 Q8N8S7	Q15942 Q96AF9
PDB IDs		2HO2 2IYB 2XQN 4MY6 5N91 5N9C 5N9P 5NAJ 5NBF 5NBX 5NC2 5NC7 5NCF 5NCG 5NCP 5ND0 5NDU 5NEG
Enriched GO Terms of Interacting Partners?
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