PACS1 and CLCN7

Number of citations of the paper that reports this interaction (PubMedID 15692563)
83

Data Source:
HPRD (in vitro)

		PACS1	CLCN7
Description		phosphofurin acidic cluster sorting protein 1	chloride voltage-gated channel 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Cytosol COPI-coated Vesicle	Nucleoplasm Lysosomal Membrane Membrane Integral Component Of Membrane Cytoplasmic Vesicle Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Ion Channel Binding	Voltage-gated Chloride Channel Activity Chloride Channel Activity ATP Binding Chloride Transmembrane Transporter Activity Antiporter Activity Transmembrane Transporter Activity
	Biological Process	Protein Localization To Golgi Apparatus Regulation Of Defense Response To Virus By Virus Protein Localization To Plasma Membrane	Response To PH Ion Transmembrane Transport Chloride Transmembrane Transport
Pathways		Nef mediated downregulation of MHC class I complex cell surface expression	Stimuli-sensing channels
Drugs
Diseases			Osteopetrosis, including: Osteopetrosis, severe neonatal or infantile forms; Osteopetrosis, intermediate forms; Osteopetrosis with renal tubular acidosis; Osteopetrosis, late-onset form type 1; Osteopetrosis, late-onset form type 2; Osteopetrosis, osteoclast poor
GWAS		Acne (severe) ( 24927181) Bipolar disorder ( 21926972 31043756) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Electroencephalogram traits ( 25387704) Obesity (early onset extreme) ( 23563609)
Interacting Genes		10 interacting genes: CLCN7 CSNK2A1 FURIN GGA3 IGF2R JUN PKD2 PPP2CA PPP2CB VAMP4	5 interacting genes: CREB3 LMNA MTDH OSTM1 PACS1
Entrez ID		55690	1186
HPRD ID		06320	04103
Ensembl ID		ENSG00000175115	ENSG00000103249
Uniprot IDs		A0A024R5H6 Q6VY07	P51798
PDB IDs
Enriched GO Terms of Interacting Partners?
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