PACS1 and VAMP4

Number of citations of the paper that reports this interaction (PubMedID 14608369)
25

Data Source:
HPRD (in vivo, in vitro)

		PACS1	VAMP4
Description		phosphofurin acidic cluster sorting protein 1	vesicle associated membrane protein 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Cytosol COPI-coated Vesicle	Golgi Membrane Lysosome Endosome Golgi Apparatus Plasma Membrane Cell Surface Transport Vesicle Integral Component Of Synaptic Vesicle Membrane Clathrin-coated Vesicle Membrane Trans-Golgi Network Membrane
	Molecular Function	Protein Binding Ion Channel Binding	Protein Binding
	Biological Process	Protein Localization To Golgi Apparatus Regulation Of Defense Response To Virus By Virus Protein Localization To Plasma Membrane	Microtubule Cytoskeleton Organization ER To Golgi Vesicle-mediated Transport Synaptic Vesicle To Endosome Fusion SNARE Complex Assembly Golgi To Plasma Membrane Protein Transport Membrane Organization Golgi Ribbon Formation Regulation Of Synaptic Vesicle Endocytosis
Pathways		Nef mediated downregulation of MHC class I complex cell surface expression	Retrograde transport at the Trans-Golgi-Network Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Bipolar disorder ( 21926972 31043756) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Electroencephalogram traits ( 25387704) Obesity (early onset extreme) ( 23563609)	Cognitive decline rate in late mild cognitive impairment ( 26252872) Hippocampal atrophy ( 25625606) Metabolite levels ( 23823483) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892)
Interacting Genes		10 interacting genes: CLCN7 CSNK2A1 FURIN GGA3 IGF2R JUN PKD2 PPP2CA PPP2CB VAMP4	11 interacting genes: AP1M1 BCL2L13 CSNK2A1 DNAJC5 KASH5 LMNA PACS1 SNAP29 STX16 STX4 STX6
Entrez ID		55690	8674
HPRD ID		06320	06070
Ensembl ID		ENSG00000175115	ENSG00000117533
Uniprot IDs		A0A024R5H6 Q6VY07	O75379 Q6IAZ3
PDB IDs
Enriched GO Terms of Interacting Partners?
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