CLCN7 and PACS1

Number of citations of the paper that reports this interaction (PubMedID 15692563)
83

Data Source:
HPRD (in vitro)

		CLCN7	PACS1
Description		chloride voltage-gated channel 7	phosphofurin acidic cluster sorting protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Lysosomal Membrane Membrane Integral Component Of Membrane Cytoplasmic Vesicle Intracellular Membrane-bounded Organelle	Golgi Apparatus Cytosol COPI-coated Vesicle
	Molecular Function	Voltage-gated Chloride Channel Activity Chloride Channel Activity ATP Binding Chloride Transmembrane Transporter Activity Antiporter Activity Transmembrane Transporter Activity	Protein Binding Ion Channel Binding
	Biological Process	Response To PH Ion Transmembrane Transport Chloride Transmembrane Transport	Protein Localization To Golgi Apparatus Regulation Of Defense Response To Virus By Virus Protein Localization To Plasma Membrane
Pathways		Stimuli-sensing channels	Nef mediated downregulation of MHC class I complex cell surface expression
Drugs
Diseases		Osteopetrosis, including: Osteopetrosis, severe neonatal or infantile forms; Osteopetrosis, intermediate forms; Osteopetrosis with renal tubular acidosis; Osteopetrosis, late-onset form type 1; Osteopetrosis, late-onset form type 2; Osteopetrosis, osteoclast poor
GWAS			Acne (severe) ( 24927181) Bipolar disorder ( 21926972 31043756) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Electroencephalogram traits ( 25387704) Obesity (early onset extreme) ( 23563609)
Interacting Genes		5 interacting genes: CREB3 LMNA MTDH OSTM1 PACS1	10 interacting genes: CLCN7 CSNK2A1 FURIN GGA3 IGF2R JUN PKD2 PPP2CA PPP2CB VAMP4
Entrez ID		1186	55690
HPRD ID		04103	06320
Ensembl ID		ENSG00000103249	ENSG00000175115
Uniprot IDs		P51798	A0A024R5H6 Q6VY07
PDB IDs
Enriched GO Terms of Interacting Partners?
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