YEATS2 and DR1

Number of citations of the paper that reports this interaction (PubMedID 22939629)
262

Data Source:
BioGRID (pull down, affinity chromatography technology, affinity chromatography technology, biochemical)

		YEATS2	DR1
Description		YEATS domain containing 2	down-regulator of transcription 1
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GO Annotations	Cellular Component	Ada2/Gcn5/Ada3 Transcription Activator Complex Mitotic Spindle	Nucleoplasm Ada2/Gcn5/Ada3 Transcription Activator Complex Negative Cofactor 2 Complex
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding TBP-class Protein Binding Histone Binding Modification-dependent Protein Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Core Promoter Binding DNA Binding Transcription Corepressor Activity Protein Binding Transcription Factor Binding TBP-class Protein Binding Protein Heterodimerization Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Histone H3 Acetylation Negative Regulation Of Transcription, DNA-templated	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Remodeling Histone H3 Acetylation Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly Positive Regulation Of Transcription By RNA Polymerase II
Pathways		HATs acetylate histones	HATs acetylate histones
Drugs
Diseases
GWAS		Systolic blood pressure ( 30224653) Visceral fat ( 30942860)	Emphysema annual change measurement in smokers (adjusted lung density) ( 31324189) HDL cholesterol levels ( 30698716) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Metabolic syndrome ( 31589552) Triglyceride levels ( 29403010) Triglyceride levels in current drinkers ( 30698716) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Urate levels ( 31578528)
Interacting Genes		2 interacting genes: DR1 TBP	8 interacting genes: DNMT3L DRAP1 NFIL3 POLE3 TBP XPO1 YEATS2 ZDHHC17
Entrez ID		55689	1810
HPRD ID		07652	03284
Ensembl ID		ENSG00000163872	ENSG00000117505
Uniprot IDs		Q9ULM3	Q01658 Q658N3
PDB IDs		5IQL 5XNV	1JFI
Enriched GO Terms of Interacting Partners?
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