DR1 and YEATS2

Number of citations of the paper that reports this interaction (PubMedID 22939629)
262

Data Source:
BioGRID (pull down, affinity chromatography technology, affinity chromatography technology, biochemical)

		DR1	YEATS2
Description		down-regulator of transcription 1	YEATS domain containing 2
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GO Annotations	Cellular Component	Nucleoplasm Ada2/Gcn5/Ada3 Transcription Activator Complex Negative Cofactor 2 Complex	Ada2/Gcn5/Ada3 Transcription Activator Complex Mitotic Spindle
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Core Promoter Binding DNA Binding Transcription Corepressor Activity Protein Binding Transcription Factor Binding TBP-class Protein Binding Protein Heterodimerization Activity	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding TBP-class Protein Binding Histone Binding Modification-dependent Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Remodeling Histone H3 Acetylation Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly Positive Regulation Of Transcription By RNA Polymerase II	Negative Regulation Of Transcription By RNA Polymerase II Histone H3 Acetylation Negative Regulation Of Transcription, DNA-templated
Pathways		HATs acetylate histones	HATs acetylate histones
Drugs
Diseases
GWAS		Emphysema annual change measurement in smokers (adjusted lung density) ( 31324189) HDL cholesterol levels ( 30698716) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Metabolic syndrome ( 31589552) Triglyceride levels ( 29403010) Triglyceride levels in current drinkers ( 30698716) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Urate levels ( 31578528)	Systolic blood pressure ( 30224653) Visceral fat ( 30942860)
Interacting Genes		8 interacting genes: DNMT3L DRAP1 NFIL3 POLE3 TBP XPO1 YEATS2 ZDHHC17	2 interacting genes: DR1 TBP
Entrez ID		1810	55689
HPRD ID		03284	07652
Ensembl ID		ENSG00000117505	ENSG00000163872
Uniprot IDs		Q01658 Q658N3	Q9ULM3
PDB IDs		1JFI	5IQL 5XNV
Enriched GO Terms of Interacting Partners?
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