DR1

Description		down-regulator of transcription 1
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GO Annotations	Cellular Component	Nucleoplasm Ada2/Gcn5/Ada3 Transcription Activator Complex Negative Cofactor 2 Complex
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Core Promoter Binding DNA Binding Transcription Corepressor Activity Protein Binding Transcription Factor Binding TBP-class Protein Binding Protein Heterodimerization Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Remodeling Histone H3 Acetylation Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly Positive Regulation Of Transcription By RNA Polymerase II
Pathways		HATs acetylate histones
Drugs
Diseases
GWAS		Emphysema annual change measurement in smokers (adjusted lung density) ( 31324189) HDL cholesterol levels ( 30698716) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Metabolic syndrome ( 31589552) Triglyceride levels ( 29403010) Triglyceride levels in current drinkers ( 30698716) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Urate levels ( 31578528)
Interacting Genes		8 interacting genes: DNMT3L DRAP1 NFIL3 POLE3 TBP XPO1 YEATS2 ZDHHC17
Entrez ID		1810
HPRD ID		03284
Ensembl ID		ENSG00000117505
Uniprot IDs		Q01658 Q658N3
PDB IDs		1JFI
Enriched GO Terms of Interacting Partners?
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