CEP55 and SUPT5H

Number of citations of the paper that reports this interaction (PubMedID 27107012)
28

Data Source:
BioGRID (two hybrid)

		CEP55	SUPT5H
Description		centrosomal protein 55	SPT5 homolog, DSIF elongation factor subunit
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GO Annotations	Cellular Component	Cell Cytoplasm Centrosome Centriole Plasma Membrane Membrane Midbody Cleavage Furrow Centriolar Satellite Intercellular Bridge Flemming Body	Nucleus Nucleoplasm DSIF Complex
	Molecular Function	Protein Binding Identical Protein Binding	Chromatin Binding RNA Binding MRNA Binding Protein Binding Enzyme Binding Protein Heterodimerization Activity
	Biological Process	Mitotic Cytokinesis Nucleus Organization Mitotic Metaphase Plate Congression Multicellular Organism Development Regulation Of Phosphatidylinositol 3-kinase Signaling Establishment Of Protein Localization Midbody Abscission Cranial Skeletal System Development	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter 7-methylguanosine MRNA Capping Positive Regulation Of Macroautophagy Negative Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Viral Transcription Negative Regulation Of MRNA Polyadenylation
Pathways			Formation of RNA Pol II elongation complex Formation of the Early Elongation Complex Formation of HIV elongation complex in the absence of HIV Tat Formation of the HIV-1 Early Elongation Complex RNA Pol II CTD phosphorylation and interaction with CE during HIV infection Formation of HIV-1 elongation complex containing HIV-1 Tat Formation of HIV-1 elongation complex containing HIV-1 Tat Pausing and recovery of Tat-mediated HIV elongation Abortive elongation of HIV-1 transcript in the absence of Tat Tat-mediated HIV elongation arrest and recovery Tat-mediated elongation of the HIV-1 transcript HIV elongation arrest and recovery Pausing and recovery of HIV elongation RNA Polymerase II Pre-transcription Events TP53 Regulates Transcription of DNA Repair Genes RNA polymerase II transcribes snRNA genes mRNA Capping RNA Polymerase II Transcription Elongation RNA Pol II CTD phosphorylation and interaction with CE
Drugs
Diseases
GWAS		High density lipoprotein cholesterol levels ( 30498476) Metabolite levels ( 23823483)
Interacting Genes		62 interacting genes: AKAP9 ANXA11 ARHGEF15 C1orf109 CCBE1 CCHCR1 CDC45 CDK1 CDSN CEP57L1 DTNB ECSIT EIF1AD FAM90A1 FBF1 FXR2 GOLGA2 GOLGA8DP HAUS1 HGS KIFC3 MAPK1 MAPK1IP1L MFAP1 MIA3 MORF4L2 NDEL1 NOS3 NTAQ1 PCNT PDCD6IP PEF1 PIN1 PLEKHG6 PLK1 POLM POM121 PPP1R16B PSEN2 PSMC2 PTPN23 PWWP3A RAB3D RBM14 RBM17 RBM22 RCOR3 RNF32 SDCBP SNRPB SNW1 SUPT5H TCL1A TEAD4 TEX11 TEX14 TFG TSG101 UBC VPS37C VPS37D WASHC3	44 interacting genes: C9orf78 CCNH CCNT1 CCNT2 CDK7 CDK9 CEP55 CSNK2A1 DBN1 DCAF6 FHL3 GOLGA2 GTF3C1 H2AX HSPB1 HTATSF1 IK IKBKG LMAN2 MAD1L1 MAML3 MNAT1 PCBD1 PHYHIP PIN1 PNO1 POLR2A PPIA PPP2R2D PRMT1 PRMT5 SAP30BP SIK1 SNX4 SSBP3 SUPT4H1 TERF1 TEX11 TLE5 XRCC5 ZBTB3 ZFYVE9 ZNF496 ZNF512B
Entrez ID		55165	6829
HPRD ID		12569	03655
Ensembl ID		ENSG00000138180	ENSG00000196235
Uniprot IDs		Q53EZ4	O00267
PDB IDs		3E1R 3WUT 3WUU 3WUV	2DO3 2E6Z 2E70 3H7H 4L1U 5OHO 5OHQ 5OIK 5U98 6EQY 6ER0 6GMH 6GML
Enriched GO Terms of Interacting Partners?
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