CEP55 and PEF1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		CEP55	PEF1
Description		centrosomal protein 55	penta-EF-hand domain containing 1
Image			No pdb structure
GO Annotations	Cellular Component	Cell Cytoplasm Centrosome Centriole Plasma Membrane Membrane Midbody Cleavage Furrow Centriolar Satellite Intercellular Bridge Flemming Body	Golgi Membrane Cytoplasm Endoplasmic Reticulum COPII Vesicle Coat Cul3-RING Ubiquitin Ligase Complex Extracellular Exosome
	Molecular Function	Protein Binding Identical Protein Binding	RNA Binding Calcium Ion Binding Protein Binding Protein Heterodimerization Activity Protein Dimerization Activity Calcium-dependent Protein Binding Protein Binding, Bridging Involved In Substrate Recognition For Ubiquitination
	Biological Process	Mitotic Cytokinesis Nucleus Organization Mitotic Metaphase Plate Congression Multicellular Organism Development Regulation Of Phosphatidylinositol 3-kinase Signaling Establishment Of Protein Localization Midbody Abscission Cranial Skeletal System Development	ER To Golgi Vesicle-mediated Transport Neural Crest Formation Neural Crest Cell Development Protein Ubiquitination COPII Vesicle Coating Response To Calcium Ion Positive Regulation Of Protein Monoubiquitination
Pathways
Drugs			Calcium Citrate Calcium Phosphate
Diseases
GWAS		High density lipoprotein cholesterol levels ( 30498476) Metabolite levels ( 23823483)	Body mass index ( 26426971) Cognitive ability ( 29186694) Cognitive ability (MTAG) ( 29186694) General cognitive ability ( 29844566) Intelligence (MTAG) ( 29326435) Severe aortic features in Marfan syndrome ( 30087447)
Interacting Genes		62 interacting genes: AKAP9 ANXA11 ARHGEF15 C1orf109 CCBE1 CCHCR1 CDC45 CDK1 CDSN CEP57L1 DTNB ECSIT EIF1AD FAM90A1 FBF1 FXR2 GOLGA2 GOLGA8DP HAUS1 HGS KIFC3 MAPK1 MAPK1IP1L MFAP1 MIA3 MORF4L2 NDEL1 NOS3 NTAQ1 PCNT PDCD6IP PEF1 PIN1 PLEKHG6 PLK1 POLM POM121 PPP1R16B PSEN2 PSMC2 PTPN23 PWWP3A RAB3D RBM14 RBM17 RBM22 RCOR3 RNF32 SDCBP SNRPB SNW1 SUPT5H TCL1A TEAD4 TEX11 TEX14 TFG TSG101 UBC VPS37C VPS37D WASHC3	14 interacting genes: ALG2 CALCOCO2 CEP55 CUL3 DAZAP2 DMRTB1 EWSR1 FOXR2 HGS KLHL12 NR0B2 PDCD6 SEC31A TFG
Entrez ID		55165	553115
HPRD ID		12569	10143
Ensembl ID		ENSG00000138180	ENSG00000162517
Uniprot IDs		Q53EZ4	A0A384MQX5 Q9UBV8
PDB IDs		3E1R 3WUT 3WUU 3WUV
Enriched GO Terms of Interacting Partners?
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