NTAQ1 and SIAH1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		NTAQ1	SIAH1
Description		N-terminal glutamine amidase 1	siah E3 ubiquitin protein ligase 1
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GO Annotations	Cellular Component	Nucleus Cytosol	Nucleus Cytoplasm Early Endosome Cytosol Plasma Membrane Beta-catenin Destruction Complex
	Molecular Function	Protein Binding Protein-N-terminal Asparagine Amidohydrolase Activity Protein-N-terminal Glutamine Amidohydrolase Activity	Ubiquitin-protein Transferase Activity Protein Binding Protein C-terminus Binding Zinc Ion Binding Ubiquitin Conjugating Enzyme Binding Identical Protein Binding Ubiquitin Protein Ligase Activity
	Biological Process	Cellular Protein Modification Process	Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Apoptotic Process Cell Cycle Spermatogenesis Nervous System Development Axon Guidance Anatomical Structure Morphogenesis Protein Catabolic Process Protein Destabilization Positive Regulation Of Apoptotic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Cellular Protein Metabolic Process Neuron Apoptotic Process Negative Regulation Of Netrin-activated Signaling Pathway Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways			Netrin-1 signaling Amyloid fiber formation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS			Height ( 28552196) Waist circumference ( 28552196)
Interacting Genes		106 interacting genes: ACTB ACTG1 AMOT AMOTL2 APIP ASL BLMH BLOC1S6 C1orf50 CAPN3 CBFA2T2 CBS CBY2 CCDC102B CCDC184 CDA CDR2 CEP55 COG6 COIL CRYAA CTBP1 CTH DAB1 DCTPP1 DHPS DNM2 EDARADD EIF2B1 ETV6 FTH1 GAS7 GMCL1 GMDS GNMT GOLGA2 HPRT1 HSD17B14 IKZF3 JAKMIP2 JUP KASH5 KCNH1 KCTD1 KLHL12 KRT31 KRTAP10-5 KRTAP10-7 KRTAP4-2 KRTAP5-9 KRTAP9-2 KRTAP9-4 LMNA LNX2 LONRF1 LZTFL1 LZTS2 MAGEA11 MARCHF10 MDFI MIF MIOS MTUS2 NAGK NCOA5 NECAB2 NME1 NPL NT5C1A NUDT14 PCBD1 PNMA1 PNMA5 PPCDC PRMT1 PRPS2 PSME3 PTS PYGM RABAC1 RBBP8 RBPMS ROPN1 RPIA SEPTIN3 SFN SIAH1 SMN1 SSX2IP STX11 TCL1A THAP1 TLE5 TMEM239 TNR TOLLIP TRAF1 TRIM27 TRIM54 TRIP13 TSC22D1 VAC14 VCP XIAP ZBTB8A ZNF341	141 interacting genes: AASDHPPT AFF1 AFF4 APC AQP1 ARMC9 ATN1 ATXN7 AXIN1 BAG1 BCL6 CACYBP CAPG CCDC198 CDC23 CDC34 CDK5R1 DAB1 DCC DDX41 DNAJC15 DNALI1 EEF1D EIF3J ELL2 EXOC3-AS1 FAM90A1 FLI1 FZD9 GAPDH GDPD5 GRM5 H4-16 HIF1AN HIPK2 HIPK3 INHA IQCN KATNAL1 KCNJ10 KHDRBS3 KIAA0319L KIAA1217 KIF1B KIF22 KIFC3 KLF10 LACTB2 LMNA MAB21L1 MAP3K5 MAPK12 MAPKBP1 MAPRE3 MOB3C MTIF3 MX1 MYD88 NANOS2 NANOS3 NECTIN2 NELFA NOL6 NTAQ1 NUMB NUMBL OPRM1 OTUB2 PARD6B PEG10 PEG3 PFKM PHC1 PHC2 PIAS2 PIAS3 PIMREG PKD1 POU2AF1 PRPF31 PRR20A PTPMT1 PUF60 PYGB QRICH1 RAB33A RAD51AP1 RAD54L2 RAPH1 RBBP8 RPL27A RPS19BP1 RXRB SDCBP SH3RF1 SLC9A3R2 SNCAIP SPATA4 SPATC1L SYP SYT7 TBC1D22B TERF2 TFDP1 TMEM43 TNK2 TOLLIP TP53BP2 TRIM23 TRIM27 TRIM7 TRIM8 TUBA1A TUBA1B TUBA3C TUBA4A TUBA8 TXN UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E3 UBE2I UBE2K UBE2L6 UBE2N UBE2V2 UPP2 USP19 UXT VAV1 ZBP1 ZCCHC10 ZCCHC13 ZFYVE21 ZMAT3 ZNF148 ZNF512B ZNF671 ZYX
Entrez ID		55093	6477
HPRD ID		07653	03736
Ensembl ID		ENSG00000156795	ENSG00000196470
Uniprot IDs		A0A3B3ITD7 A0A3B3ITI2 E5RHC2 Q96HA8	Q8IUQ4
PDB IDs		3C9Q 4W79	2A25 4C9Z 4CA1 4I7B 4I7C 4I7D 4X3G 5WZZ
Enriched GO Terms of Interacting Partners?
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