NTAQ1 and RBBP8

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		NTAQ1	RBBP8
Description		N-terminal glutamine amidase 1	RB binding protein 8, endonuclease
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GO Annotations	Cellular Component	Nucleus Cytosol	Nucleus Nucleoplasm Transcriptional Repressor Complex Site Of Double-strand Break Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Protein-N-terminal Asparagine Amidohydrolase Activity Protein-N-terminal Glutamine Amidohydrolase Activity	Single-stranded DNA Endodeoxyribonuclease Activity Y-form DNA Binding Double-strand/single-strand DNA Junction Binding RNA Polymerase II Repressing Transcription Factor Binding Damaged DNA Binding Double-stranded DNA Binding Single-stranded DNA Binding Transcription Corepressor Activity Protein Binding Identical Protein Binding Flap-structured DNA Binding
	Biological Process	Cellular Protein Modification Process	G1/S Transition Of Mitotic Cell Cycle Double-strand Break Repair Via Homologous Recombination DNA Double-strand Break Processing Blastocyst Hatching DNA Replication DNA Repair Regulation Of Transcription By RNA Polymerase II DNA Double-strand Break Processing Involved In Repair Via Single-strand Annealing Response To Estradiol Cell Division Meiotic Cell Cycle Negative Regulation Of G0 To G1 Transition Nucleic Acid Phosphodiester Bond Hydrolysis Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Nucleic Acid-templated Transcription
Pathways			HDR through Single Strand Annealing (SSA) HDR through MMEJ (alt-NHEJ) HDR through Homologous Recombination (HRR) Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) Resolution of D-loop Structures through Holliday Junction Intermediates Homologous DNA Pairing and Strand Exchange Processing of DNA double-strand break ends Presynaptic phase of homologous DNA pairing and strand exchange Regulation of TP53 Activity through Phosphorylation G2/M DNA damage checkpoint Transcriptional Regulation by E2F6 Meiotic recombination
Drugs
Diseases			Seckel syndrome
GWAS			Eosinophil percentage of white cells ( 27863252) Height ( 25429064 18391951) Intracranial aneurysm ( 20364137) Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy) ( 27418160) Late-onset myasthenia gravis ( 26562150) Lung function (FEV1) ( 30061609) Scalp hair shape ( 26926045) Tuberculosis ( 20694014)
Interacting Genes		106 interacting genes: ACTB ACTG1 AMOT AMOTL2 APIP ASL BLMH BLOC1S6 C1orf50 CAPN3 CBFA2T2 CBS CBY2 CCDC102B CCDC184 CDA CDR2 CEP55 COG6 COIL CRYAA CTBP1 CTH DAB1 DCTPP1 DHPS DNM2 EDARADD EIF2B1 ETV6 FTH1 GAS7 GMCL1 GMDS GNMT GOLGA2 HPRT1 HSD17B14 IKZF3 JAKMIP2 JUP KASH5 KCNH1 KCTD1 KLHL12 KRT31 KRTAP10-5 KRTAP10-7 KRTAP4-2 KRTAP5-9 KRTAP9-2 KRTAP9-4 LMNA LNX2 LONRF1 LZTFL1 LZTS2 MAGEA11 MARCHF10 MDFI MIF MIOS MTUS2 NAGK NCOA5 NECAB2 NME1 NPL NT5C1A NUDT14 PCBD1 PNMA1 PNMA5 PPCDC PRMT1 PRPS2 PSME3 PTS PYGM RABAC1 RBBP8 RBPMS ROPN1 RPIA SEPTIN3 SFN SIAH1 SMN1 SSX2IP STX11 TCL1A THAP1 TLE5 TMEM239 TNR TOLLIP TRAF1 TRIM27 TRIM54 TRIP13 TSC22D1 VAC14 VCP XIAP ZBTB8A ZNF341	37 interacting genes: ATM BARD1 BRCA1 CLU CTBP1 CUL3 DNA2 EEF1A1 FXR2 FZR1 HID1 IGFBP7 IKBKG IKZF1 IKZF3 KLHL15 LIMS1 LMO1 LMO2 LMO4 MAP2K4 NTAQ1 PCNA PIN1 PRKDC PRRG4 RAF1 RB1 RBL1 RBL2 RGS17 SIAH1 SIAH2 TGIF2 TMEM54 TOPBP1 USP4
Entrez ID		55093	5932
HPRD ID		07653	04990
Ensembl ID		ENSG00000156795	ENSG00000101773
Uniprot IDs		A0A3B3ITD7 A0A3B3ITI2 E5RHC2 Q96HA8	A0A024RC34 Q99708
PDB IDs		3C9Q 4W79	2L4Z 4D2H
Enriched GO Terms of Interacting Partners?
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