GIPC2 and IGSF21

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
HPRD (two hybrid)

		GIPC2	IGSF21
Description		GIPC PDZ domain containing family member 2	immunoglobin superfamily member 21
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Extracellular Exosome	Adherens Junction Anchored Component Of External Side Of Plasma Membrane Presynaptic Membrane Postsynaptic Membrane Inhibitory Synapse
	Molecular Function	Molecular_function Protein Binding Identical Protein Binding	Signaling Receptor Activity Protein Homodimerization Activity Cell Adhesion Molecule Binding
	Biological Process	Biological_process	Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Synapse Maturation
Pathways
Drugs
Diseases
GWAS		Body mass index ( 29273807) End-stage kidney disease ( 31178898) Hand grip strength ( 29691431) Height ( 20881960 25282103) Hip circumference ( 25673412) Lung adenocarcinoma ( 28604730) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730) Post bronchodilator FEV1 ( 26634245) Severe influenza A (H1N1) infection ( 26379185)	Atypical femoral fracture in phosphonate treatment ( 31006051) Cobalt levels ( 26025379) Diabetic retinopathy ( 21441570) Erectile dysfunction and prostate cancer treatment ( 20932654) Hippocampal volume in Alzheimer's disease dementia ( 29274321) Pre-treatment viral load in HIV-1 infection ( 31219150) Response to cognitive-behavioural therapy in anxiety disorder ( 31123309) Serum bilirubin levels x sex interaction in metabolic syndrome ( 30621171) Survival in pancreatic cancer ( 28470677)
Interacting Genes		7 interacting genes: FZD3 IGSF21 PTN SETDB1 SP100 UNC119 ZBTB26	32 interacting genes: ALDH2 ANXA3 ATF3 BCR BTBD2 CRCT1 DGKD EPB41L3 ERH ETHE1 GADD45A GIPC2 GSK3B GSTM4 HSPB1 KRAS MAD2L1BP NACA NREP PAEP PAFAH1B3 PCDHA4 PRMT1 PSMD11 RPP14 S100A8 SEPHS1 SERPINB9 SULT1E1 TMSB4X TRBV2 UBE2V2
Entrez ID		54810	84966
HPRD ID		17040	11309
Ensembl ID		ENSG00000137960	ENSG00000117154
Uniprot IDs		A0A384P5H2 Q8TF65	Q96ID5
PDB IDs		3GGE
Enriched GO Terms of Interacting Partners?
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