MPHOSPH8 and RANBP9

Number of citations of the paper that reports this interaction (PubMedID 12559565)
27

Data Source:
HPRD (two hybrid)

		MPHOSPH8	RANBP9
Description		M-phase phosphoprotein 8	RAN binding protein 9
Image
GO Annotations	Cellular Component	Nuclear Nucleosome Heterochromatin Nucleus Nucleoplasm Nuclear Heterochromatin Nucleolus Cytoplasm Cytosol Plasma Membrane	Ubiquitin Ligase Complex Nucleus Cytoplasm Cytosol Microtubule Associated Complex Plasma Membrane
	Molecular Function	Chromatin Binding Protein Binding Methylated Histone Binding	Protein Binding Ran GTPase Binding Enzyme Binding
	Biological Process	Regulation Of DNA Methylation Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Methylation-dependent Chromatin Silencing	MAPK Cascade Microtubule Nucleation Axon Guidance Protein-containing Complex Assembly Negative Regulation Of ERK1 And ERK2 Cascade
Pathways			L1CAM interactions RAF/MAP kinase cascade MET activates RAS signaling
Drugs
Diseases
GWAS			Breast cancer ( 29059683 23535729)
Interacting Genes		5 interacting genes: H3C1 MTRNR2L1 RANBP9 SH3BP4 SIRT1	56 interacting genes: ADAP1 ADAP2 APC AR ATM AXL BACE1 BRCA1 CACNA1G CALB1 CBS CCND1 CDK11B CLEC7A DDX4 DISC1 DYRK1B ENTPD1 ESR1 EXOC2 FMR1 HIPK2 HMBS HNF4G ITGAL ITGB2 L1CAM LMNA MAPK6 MET MKLN1 MPHOSPH8 NCOA6 NCOR2 PPARD PPARG PPP1CA PRKACA RAF1 RAN S100A7 SMAD2 SMAD3 SMAD9 SOS1 SPOP SPP1 TFRC THRA THRB TP53 TP73 UCHL1 USP11 WNK1 YPEL5
Entrez ID		54737	10048
HPRD ID		13682	04835
Ensembl ID		ENSG00000196199	ENSG00000010017
Uniprot IDs		Q99549	A0A024QZW3 Q96S59
PDB IDs		3LWE 3QO2 3R93 3SVM	5JI7 5JI9 5JIU
Enriched GO Terms of Interacting Partners?
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