RANBP9 and CLEC7A

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		RANBP9	CLEC7A
Description		RAN binding protein 9	C-type lectin domain containing 7A
Image			No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Cytoplasm Cytosol Microtubule Associated Complex Plasma Membrane	Cytoplasm Plasma Membrane Cell Surface Integral Component Of Membrane
	Molecular Function	Protein Binding Ran GTPase Binding Enzyme Binding	(1->3)-beta-D-glucan Binding Protein Binding Carbohydrate Binding Pattern Recognition Receptor Activity MHC Protein Binding Metal Ion Binding
	Biological Process	MAPK Cascade Microtubule Nucleation Axon Guidance Protein-containing Complex Assembly Negative Regulation Of ERK1 And ERK2 Cascade	Phagocytosis, Recognition Inflammatory Response Cell Recognition Positive Regulation Of Cell Proliferation Carbohydrate Mediated Signaling Positive Regulation Of Gene Expression Detection Of Fungus Positive Regulation Of Cell Migration Positive Regulation Of Protein Complex Assembly Detection Of Molecule Of Fungal Origin Positive Regulation Of Interleukin-1 Beta Production Positive Regulation Of Superoxide Anion Generation T Cell Activation Positive Regulation Of Tumor Necrosis Factor Biosynthetic Process Defense Response To Protozoan Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Interferon-gamma Biosynthetic Process Positive Regulation Of Interleukin-10 Biosynthetic Process Positive Regulation Of Interleukin-12 Biosynthetic Process Positive Regulation Of Interleukin-2 Biosynthetic Process Innate Immune Response Positive Regulation Of Interleukin-6 Biosynthetic Process Positive Regulation Of Interleukin-8 Biosynthetic Process Positive Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Phagocytosis Positive Regulation Of Lymphocyte Activation Positive Regulation Of Killing Of Cells Of Other Organism Positive Regulation Of Respiratory Burst Cellular Response To Molecule Of Fungal Origin Positive Regulation Of Monocyte Chemotactic Protein-1 Production Positive Regulation Of Wound Healing Positive Regulation Of Cytokine Production Involved In Inflammatory Response Positive Regulation Of Cell Maturation
Pathways		L1CAM interactions RAF/MAP kinase cascade MET activates RAS signaling	CLEC7A (Dectin-1) signaling CLEC7A (Dectin-1) signaling
Drugs
Diseases			Chronic Mucocutaneous Candidiasis (CMC); Familial candidiasis (CANDF)
GWAS		Breast cancer ( 29059683 23535729)
Interacting Genes		56 interacting genes: ADAP1 ADAP2 APC AR ATM AXL BACE1 BRCA1 CACNA1G CALB1 CBS CCND1 CDK11B CLEC7A DDX4 DISC1 DYRK1B ENTPD1 ESR1 EXOC2 FMR1 HIPK2 HMBS HNF4G ITGAL ITGB2 L1CAM LMNA MAPK6 MET MKLN1 MPHOSPH8 NCOA6 NCOR2 PPARD PPARG PPP1CA PRKACA RAF1 RAN S100A7 SMAD2 SMAD3 SMAD9 SOS1 SPOP SPP1 TFRC THRA THRB TP53 TP73 UCHL1 USP11 WNK1 YPEL5	19 interacting genes: ADAM33 AIP BNIP3 BNIP3L CALM3 FAM3A HSPD1 IL1RL1 JAGN1 KTN1 NINJ2 OCLN PTTG1IP RANBP9 RHOU SMIM3 SYNE4 TMEM79 TMPRSS4
Entrez ID		10048	64581
HPRD ID		04835	08396
Ensembl ID		ENSG00000010017	ENSG00000172243
Uniprot IDs		A0A024QZW3 Q96S59	A0A024RAN9 A0A0S2Z5Q1 Q68D78 Q9BXN2
PDB IDs		5JI7 5JI9 5JIU
Enriched GO Terms of Interacting Partners?
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