MPHOSPH8 and SH3BP4

Number of citations of the paper that reports this interaction (PubMedID 18654987)
16

Data Source:
BioGRID (two hybrid)

		MPHOSPH8	SH3BP4
Description		M-phase phosphoprotein 8	SH3 domain binding protein 4
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Nucleosome Heterochromatin Nucleus Nucleoplasm Nuclear Heterochromatin Nucleolus Cytoplasm Cytosol Plasma Membrane	Nucleus Cytoplasm Clathrin-coated Pit Clathrin-coated Vesicle Extracellular Exosome
	Molecular Function	Chromatin Binding Protein Binding Methylated Histone Binding	GDP-dissociation Inhibitor Activity Protein Binding Ras GTPase Binding Identical Protein Binding
	Biological Process	Regulation Of DNA Methylation Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Methylation-dependent Chromatin Silencing	Endocytosis Negative Regulation Of Cell Proliferation Positive Regulation Of Autophagy Negative Regulation Of Cell Growth Negative Regulation Of TOR Signaling Negative Regulation Of GTPase Activity Amino Acid Import Regulation Of Catalytic Activity Protein Localization To Lysosome Cellular Response To Amino Acid Stimulus
Pathways			Amino acids regulate mTORC1
Drugs
Diseases
GWAS			Depression in smokers ( 30219690) Dialysis-related mortality ( 21546767) Mean corpuscular hemoglobin ( 29403010) Mean corpuscular volume ( 29403010) Obstetric antiphospholipid syndrome ( 28424481) Orofacial clefts ( 22419666)
Interacting Genes		5 interacting genes: H3C1 MTRNR2L1 RANBP9 SH3BP4 SIRT1	22 interacting genes: C2orf73 CCT3 CEP78 CIZ1 DNAJA4 FKBP4 GAPDHS GIPC1 GKAP1 HSPA5 MPHOSPH8 MRGBP NFU1 PLEKHA1 PRR14 PSMA1 TCP1 TTC1 TXNL1 YWHAE YWHAG ZBTB37
Entrez ID		54737	23677
HPRD ID		13682	09285
Ensembl ID		ENSG00000196199	ENSG00000130147
Uniprot IDs		Q99549	Q9P0V3
PDB IDs		3LWE 3QO2 3R93 3SVM
Enriched GO Terms of Interacting Partners?
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