CIAO2B and USP4

Number of citations of the paper that reports this interaction (PubMedID 23022198)
4

Data Source:
BioGRID (two hybrid)

		CIAO2B	USP4
Description		cytosolic iron-sulfur assembly component 2B	ubiquitin specific peptidase 4
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Spindle Cytosol MMXD Complex CIA Complex	Nucleus Cytoplasm Lysosome Cytosol Plasma Membrane
	Molecular Function	Protein Binding	Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Adenosine Receptor Binding Thiol-dependent Ubiquitinyl Hydrolase Activity Identical Protein Binding Metal Ion Binding
	Biological Process	Chromosome Segregation Iron-sulfur Cluster Assembly Protein Maturation By Iron-sulfur Cluster Transfer Protein Maturation By [4Fe-4S] Cluster Transfer	Spliceosomal Tri-snRNP Complex Assembly Ubiquitin-dependent Protein Catabolic Process Protein Deubiquitination Negative Regulation Of Protein Ubiquitination Regulation Of Protein Stability Protein Localization To Cell Surface
Pathways		Cytosolic iron-sulfur cluster assembly	TNFR1-induced proapoptotic signaling Regulation of TNFR1 signaling TNFR1-induced NFkappaB signaling pathway Ub-specific processing proteases
Drugs
Diseases
GWAS			Blood protein levels ( 28240269) Crohn's disease ( 28067908) Glycated hemoglobin levels ( 28898252) High light scatter reticulocyte percentage of red cells ( 27863252) Household income (MTAG) ( 31844048) Inflammatory bowel disease ( 28067908 23128233) Intelligence (MTAG) ( 29326435) Reticulocyte count ( 27863252) Reticulocyte fraction of red cells ( 27863252) Sleep duration (short sleep) ( 30846698) Ulcerative colitis ( 28067908 25082827)
Interacting Genes		5 interacting genes: CIAO1 ERRFI1 MTNR1A PAXIP1 USP4	47 interacting genes: AKT1 ANXA7 ASS1 ATP1B1 ATP1B3 BRAP CDKN1A CIAO2B HDAC2 HUWE1 IGKV2D-29 IRF4 LAMA5 LGALS1 NLK NOLC1 NPC2 PCNA PDK1 PGM1 PLA2G2A PLOD1 PPIA PRPF3 PSAP PSMA6 PSMC5 PSMD11 RB1 RBBP8 RBL1 RBL2 RCC1 RHEB RNPS1 SMAD4 SMN1 TK1 TP53BP2 TRAF2 TRIM21 TRIM54 TRIM55 TRIM63 UBC USP21 USP28
Entrez ID		51647	7375
HPRD ID		13033	04598
Ensembl ID		ENSG00000166595	ENSG00000114316
Uniprot IDs		Q9Y3D0	A0A024R2X6 A1LPW7 Q08AK7 Q13107
PDB IDs			2Y6E 5CTR
Enriched GO Terms of Interacting Partners?
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