ORM1 and GLUD1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		ORM1	GLUD1
Description		orosomucoid 1	glutamate dehydrogenase 1
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Platelet Alpha Granule Lumen Specific Granule Lumen Collagen-containing Extracellular Matrix Extracellular Exosome Blood Microparticle Tertiary Granule Lumen	Cytoplasm Mitochondrion Mitochondrial Matrix
	Molecular Function	Protein Binding	Glutamate Dehydrogenase (NAD+) Activity Glutamate Dehydrogenase [NAD(P)+] Activity Protein Binding ATP Binding GTP Binding Identical Protein Binding ADP Binding NAD+ Binding Leucine Binding
	Biological Process	Platelet Degranulation Regulation Of Immune System Process Acute-phase Response Inflammatory Response Negative Regulation Of Interleukin-6 Production Negative Regulation Of Tumor Necrosis Factor Production Neutrophil Degranulation Positive Regulation Of Interleukin-1 Secretion Positive Regulation Of Interleukin-1 Beta Secretion Positive Regulation Of Tumor Necrosis Factor Secretion	Glutamate Biosynthetic Process Glutamate Catabolic Process Glutamine Metabolic Process Cellular Amino Acid Biosynthetic Process Substantia Nigra Development Positive Regulation Of Insulin Secretion Oxidation-reduction Process Tricarboxylic Acid Metabolic Process
Pathways		Platelet degranulation Neutrophil degranulation	Transcriptional activation of mitochondrial biogenesis Glutamate and glutamine metabolism
Drugs		Amsacrine Lidocaine Progesterone Chlorpromazine Oxycodone Dipyridamole Thalidomide	Glutamic Acid NADH Hexachlorophene Guanosine-5'-Triphosphate Aluminum chloride
Diseases
GWAS		End-stage coagulation ( 23381943) Thrombin generation potential phenotypes ( 24357727) Tourette syndrome ( 22889924)
Interacting Genes		9 interacting genes: ALB BLVRB CCR5 GLUD1 GSDMB PIK3R3 SERPINE1 TMEM37 TP63	12 interacting genes: ASGR2 CRP DYNLL1 GOT2 HPX HSD17B10 LSM1 NR4A1 ORM1 SEC62 STAT5A VTN
Entrez ID		5004	2746
HPRD ID		00724	11748
Ensembl ID		ENSG00000229314	ENSG00000148672
Uniprot IDs		P02763	E9KL48 P00367
PDB IDs		3KQ0	1L1F 1NR1 6DQG
Enriched GO Terms of Interacting Partners?
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