GLUD1 and VTN

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		GLUD1	VTN
Description		glutamate dehydrogenase 1	vitronectin
Image
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Matrix	Extracellular Region Basement Membrane Extracellular Space Endoplasmic Reticulum Golgi Lumen Intracellular Membrane-bounded Organelle Rough Endoplasmic Reticulum Lumen Collagen-containing Extracellular Matrix Extracellular Exosome Alphav-beta3 Integrin-vitronectin Complex Blood Microparticle
	Molecular Function	Glutamate Dehydrogenase (NAD+) Activity Glutamate Dehydrogenase [NAD(P)+] Activity Protein Binding ATP Binding GTP Binding Identical Protein Binding ADP Binding NAD+ Binding Leucine Binding	Scavenger Receptor Activity Integrin Binding Extracellular Matrix Structural Constituent Protein Binding Collagen Binding Heparin Binding Polysaccharide Binding Identical Protein Binding Extracellular Matrix Binding
	Biological Process	Glutamate Biosynthetic Process Glutamate Catabolic Process Glutamine Metabolic Process Cellular Amino Acid Biosynthetic Process Substantia Nigra Development Positive Regulation Of Insulin Secretion Oxidation-reduction Process Tricarboxylic Acid Metabolic Process	Endocytosis Immune Response Cell Adhesion Cell-matrix Adhesion Positive Regulation Of Cell-substrate Adhesion Negative Regulation Of Endopeptidase Activity Positive Regulation Of Smooth Muscle Cell Migration Cell Migration Negative Regulation Of Blood Coagulation Extracellular Matrix Organization Regulation Of Complement Activation Positive Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Protein Binding Cell Adhesion Mediated By Integrin Endodermal Cell Differentiation Positive Regulation Of Receptor-mediated Endocytosis Oligodendrocyte Differentiation Positive Regulation Of Peptidyl-tyrosine Phosphorylation Protein Polymerization Smooth Muscle Cell-matrix Adhesion Positive Regulation Of Wound Healing Liver Regeneration
Pathways		Transcriptional activation of mitochondrial biogenesis Glutamate and glutamine metabolism	Molecules associated with elastic fibres Integrin cell surface interactions Syndecan interactions ECM proteoglycans ECM proteoglycans Regulation of Complement cascade
Drugs		Glutamic Acid NADH Hexachlorophene Guanosine-5'-Triphosphate Aluminum chloride	Abciximab Zinc Copper
Diseases
GWAS			Advanced age-related macular degeneration ( 26691988) Blood protein levels ( 30072576 29875488 28240269) Heel bone mineral density ( 30598549) LDL cholesterol ( 30275531) Osteoprotegerin levels ( 25080503)
Interacting Genes		12 interacting genes: ASGR2 CRP DYNLL1 GOT2 HPX HSD17B10 LSM1 NR4A1 ORM1 SEC62 STAT5A VTN	43 interacting genes: ADH5 ADTRP AMPH APP CBX1 CD247 CKS2 COPS5 CRADD CSNK2A1 EGF ETV7 FGF2 FGG GEM GLUD1 GOPC HGF IGF2 IGFBP5 ITGA8 ITGB3 ITGB6 ITGB8 KNG1 LACRT LNX2 PLAUR POMC PRDX4 PRKACA PRKCA PRKCB PRKCG PVR RHOXF1 RPL13A SERPINE1 SIX1 TGFB1 TGFB2 TNFRSF11B VEGFA
Entrez ID		2746	7448
HPRD ID		11748	01902
Ensembl ID		ENSG00000148672	ENSG00000109072
Uniprot IDs		E9KL48 P00367	D9ZGG2 P04004
PDB IDs		1L1F 1NR1 6DQG	1OC0 1S4G 1SSU 2JQ8 3BT1 3BT2 4K24 6O5E
Enriched GO Terms of Interacting Partners?
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