OPRK1 and GABARAPL1

Number of citations of the paper that reports this interaction (PubMedID 16431922)
40

Data Source:
HPRD (in vivo, two hybrid, in vitro)

		OPRK1	GABARAPL1
Description		opioid receptor kappa 1	GABA type A receptor associated protein like 1
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GO Annotations	Cellular Component	Nucleoplasm Cytosol Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane Neuron Projection Synapse	Autophagosome Membrane Intracellular Mitochondrion Autophagosome Endoplasmic Reticulum Golgi Apparatus Cytosol Microtubule Cytoplasmic Vesicle Membrane Dendrite Membrane Dendrite Cytoplasm Cell Body
	Molecular Function	G Protein-coupled Receptor Activity Opioid Receptor Activity Protein Binding Dynorphin Receptor Activity Peptide Binding Neuropeptide Binding	Protein Binding Microtubule Binding Tat Protein Binding Ubiquitin Protein Ligase Binding Beta-tubulin Binding GABA Receptor Binding
	Biological Process	Immune Response G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Chemical Synaptic Transmission Sensory Perception Locomotory Behavior Sensory Perception Of Pain Adenylate Cyclase-inhibiting Opioid Receptor Signaling Pathway Opioid Receptor Signaling Pathway Regulation Of Saliva Secretion Defense Response To Virus	Autophagosome Assembly Autophagy Of Mitochondrion Cellular Response To Nitrogen Starvation Macroautophagy Autophagosome Maturation
Pathways		Peptide ligand-binding receptors G alpha (i) signalling events MECP2 regulates neuronal receptors and channels	Macroautophagy
Drugs		Tramadol Morphine Codeine Amitriptyline Hydromorphone Mirtazapine Progesterone Pethidine Oxycodone Dextromethorphan Butorphanol Dextropropoxyphene Pentazocine Naltrexone Sufentanil Fentanyl Menthol Loperamide Nalbuphine Levorphanol Remifentanil Buprenorphine Naloxone Dezocine Ketamine 3-Methylthiofentanyl Heroin Etorphine Carfentanil Diprenorphine Dihydromorphine 3-Methylfentanyl V1003 Asimadoline CR665 ADL 10-0101 Mianserin Tapentadol Nalmefene Alvimopan Ketobemidone Methylnaltrexone Eluxadoline Propoxyphene napsylate Naldemedine
Diseases
GWAS		IgE levels in asthmatics (D.p. specific) ( 23967269) Modic changes ( 30808802)
Interacting Genes		5 interacting genes: GABARAPL1 GNA15 GPRASP1 OPRD1 SLC9A3R1	47 interacting genes: AHNAK2 AMBRA1 ANK2 ATG13 ATG4A ATG4D CALCOCO2 CUL3 DVL2 FUNDC1 KBTBD7 KRTAP10-3 KRTAP10-7 KRTAP10-9 KXD1 MAPK15 MEFV NEDD4 OPRK1 OPTN RABGAP1 RABGAP1L RB1CC1 RETREG3 SCYL3 SNCA SQSTM1 SRPK1 SRPK2 TAX1BP1 TBC1D1 TBC1D10A TBC1D10B TBC1D16 TBC1D17 TBC1D2 TBC1D25 TBC1D2B TBC1D5 TBC1D7 TBC1D9 TBC1D9B TNIP1 TRIM21 ULK1 VDR WDFY3
Entrez ID		4986	23710
HPRD ID		01309	07601
Ensembl ID		ENSG00000082556	ENSG00000139112
Uniprot IDs		A0A5F9ZI09 P41145	A0A024RAP5 Q9H0R8
PDB IDs		2A0D 2IQN 4DJH 6B73	2L8J 2R2Q 5DPT 5LXH 5LXI 6HOI 6HOL
Enriched GO Terms of Interacting Partners?
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