GABARAPL1 and TBC1D5

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid, pull down)

		GABARAPL1	TBC1D5
Description		GABA type A receptor associated protein like 1	TBC1 domain family member 5
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GO Annotations	Cellular Component	Autophagosome Membrane Intracellular Mitochondrion Autophagosome Endoplasmic Reticulum Golgi Apparatus Cytosol Microtubule Cytoplasmic Vesicle Membrane Dendrite Membrane Dendrite Cytoplasm Cell Body	Autophagosome Golgi Apparatus Cytosol Endosome Membrane AP-2 Adaptor Complex Retromer Complex Intracellular Membrane-bounded Organelle Atg1/ULK1 Kinase Complex
	Molecular Function	Protein Binding Microtubule Binding Tat Protein Binding Ubiquitin Protein Ligase Binding Beta-tubulin Binding GABA Receptor Binding	GTPase Activator Activity Protein Binding Rab GTPase Binding AP-2 Adaptor Complex Binding Protein-containing Complex Binding Retromer Complex Binding
	Biological Process	Autophagosome Assembly Autophagy Of Mitochondrion Cellular Response To Nitrogen Starvation Macroautophagy Autophagosome Maturation	Positive Regulation Of Receptor Internalization Intracellular Protein Transport Autophagy Macroautophagy Retrograde Transport, Endosome To Golgi Response To Starvation Activation Of GTPase Activity Regulation Of Cilium Assembly
Pathways		Macroautophagy
Drugs
Diseases
GWAS			General risk tolerance (MTAG) ( 30643258) Height ( 28552196) Mean platelet volume ( 27863252) Midgestational circulating levels of PBDEs (fetal genetic effect) ( 28235828) Platelet count ( 27863252) Platelet distribution width ( 27863252) Plateletcrit ( 27863252) Schizophrenia ( 28991256 25056061 29483656) Self-reported risk-taking behaviour ( 30271922)
Interacting Genes		47 interacting genes: AHNAK2 AMBRA1 ANK2 ATG13 ATG4A ATG4D CALCOCO2 CUL3 DVL2 FUNDC1 KBTBD7 KRTAP10-3 KRTAP10-7 KRTAP10-9 KXD1 MAPK15 MEFV NEDD4 OPRK1 OPTN RABGAP1 RABGAP1L RB1CC1 RETREG3 SCYL3 SNCA SQSTM1 SRPK1 SRPK2 TAX1BP1 TBC1D1 TBC1D10A TBC1D10B TBC1D16 TBC1D17 TBC1D2 TBC1D25 TBC1D2B TBC1D5 TBC1D7 TBC1D9 TBC1D9B TNIP1 TRIM21 ULK1 VDR WDFY3	7 interacting genes: AP2M1 ATXN1 EIF1AD GABARAPL1 GABARAPL2 MAP1LC3A UBC
Entrez ID		23710	9779
HPRD ID		07601	10262
Ensembl ID		ENSG00000139112	ENSG00000131374
Uniprot IDs		A0A024RAP5 Q9H0R8	B9A6K1 Q92609
PDB IDs		2L8J 2R2Q 5DPT 5LXH 5LXI 6HOI 6HOL	5GTU
Enriched GO Terms of Interacting Partners?
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