OPRK1 and GPRASP1

Number of citations of the paper that reports this interaction (PubMedID 15086532)
34

Data Source:
BioGRID (pull down)

		OPRK1	GPRASP1
Description		opioid receptor kappa 1	G protein-coupled receptor associated sorting protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane Neuron Projection Synapse	Cytosol
	Molecular Function	G Protein-coupled Receptor Activity Opioid Receptor Activity Protein Binding Dynorphin Receptor Activity Peptide Binding Neuropeptide Binding	Protein Binding
	Biological Process	Immune Response G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Chemical Synaptic Transmission Sensory Perception Locomotory Behavior Sensory Perception Of Pain Adenylate Cyclase-inhibiting Opioid Receptor Signaling Pathway Opioid Receptor Signaling Pathway Regulation Of Saliva Secretion Defense Response To Virus	Endosome To Lysosome Transport G Protein-coupled Receptor Catabolic Process
Pathways		Peptide ligand-binding receptors G alpha (i) signalling events MECP2 regulates neuronal receptors and channels
Drugs		Tramadol Morphine Codeine Amitriptyline Hydromorphone Mirtazapine Progesterone Pethidine Oxycodone Dextromethorphan Butorphanol Dextropropoxyphene Pentazocine Naltrexone Sufentanil Fentanyl Menthol Loperamide Nalbuphine Levorphanol Remifentanil Buprenorphine Naloxone Dezocine Ketamine 3-Methylthiofentanyl Heroin Etorphine Carfentanil Diprenorphine Dihydromorphine 3-Methylfentanyl V1003 Asimadoline CR665 ADL 10-0101 Mianserin Tapentadol Nalmefene Alvimopan Ketobemidone Methylnaltrexone Eluxadoline Propoxyphene napsylate Naldemedine
Diseases
GWAS		IgE levels in asthmatics (D.p. specific) ( 23967269) Modic changes ( 30808802)
Interacting Genes		5 interacting genes: GABARAPL1 GNA15 GPRASP1 OPRD1 SLC9A3R1	47 interacting genes: ADRB1 ADRB2 AGTR1 ATXN7 C8orf33 CALCR CHRM1 CHRM2 CHRM3 CHRM4 CHRM5 CRIP1 CXCR2 F2R F2RL1 GLP1R GLYAT GRM1 GRM5 GRM8 HGH1 HMOX2 HTR7 LAMTOR5 LRP2 MAP7D1 MLNR MTF2 OFD1 OPRD1 OPRK1 OPRL1 OPRM1 OXTR PBK PER1 PFDN1 SNAPIN STMN2 TAC3 TACR1 TACR2 TACR3 TBXA2R TFG TRAF4 VIPR1
Entrez ID		4986	9737
HPRD ID		01309	02333
Ensembl ID		ENSG00000082556	ENSG00000198932
Uniprot IDs		A0A5F9ZI09 P41145	Q5JY77
PDB IDs		2A0D 2IQN 4DJH 6B73
Enriched GO Terms of Interacting Partners?
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