ATOX1 and FAM118A

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		ATOX1	FAM118A
Description		antioxidant 1 copper chaperone	family with sequence similarity 118 member A
Image			No pdb structure
GO Annotations	Cellular Component	Cell Cytosol	Integral Component Of Membrane
	Molecular Function	Copper Ion Binding Protein Binding Metallochaperone Activity Copper Chaperone Activity Copper-dependent Protein Binding ATPase Binding	Protein Binding Identical Protein Binding
	Biological Process	Copper Ion Transport Cellular Copper Ion Homeostasis Response To Oxidative Stress Negative Regulation Of Apoptotic Process Copper Ion Export
Pathways		Detoxification of Reactive Oxygen Species Ion influx/efflux at host-pathogen interface
Drugs		Cisplatin Sucrose Benzamidine
Diseases
GWAS		Creatinine levels ( 29403010) Glomerular filtration rate ( 29403010) Systolic blood pressure change trajectories ( 27980656)	Birth weight ( 31043758) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Chronotype ( 30696823) Dentures ( 31235808) Heel bone mineral density ( 30598549) Height ( 31562340) Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808) Peanut allergy (maternal genetic effects) ( 29489655)
Interacting Genes		6 interacting genes: ATP7A ATP7B CFAP410 FAM118A FKBP4 GGPS1	10 interacting genes: AIDA ATOX1 FAM118B GLRX3 LNX1 MOB1A MOB3C SDCBP WDR4 ZNF451
Entrez ID		475	55007
HPRD ID		03779	07936
Ensembl ID		ENSG00000177556	ENSG00000100376
Uniprot IDs		O00244	A0A024R4V3 Q9NWS6
PDB IDs		1FE0 1FE4 1FEE 1TL4 1TL5 2K1R 2LQ9 3CJK 3IWL 3IWX 4QOT 4YDX 4YEA 5F0W 5T7L
Enriched GO Terms of Interacting Partners?
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