NEDD8 and N4BP1

Number of citations of the paper that reports this interaction (PubMedID 30659753)
3

Data Source:
BioGRID (pull down)

		NEDD8	N4BP1
Description		NEDD8 ubiquitin like modifier	NEDD4 binding protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Cell Nucleus Nucleoplasm Cytoplasm Cytosol Extracellular Exosome	Nucleolus PML Body
	Molecular Function	Protein Binding Protein Tag Ubiquitin Protein Ligase Binding	Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Cellular Protein Modification Process Proteolysis Ubiquitin-dependent Protein Catabolic Process Cellular Iron Ion Homeostasis Protein Localization Anatomical Structure Morphogenesis Response To Organic Cyclic Compound Protein Ubiquitination Protein Deubiquitination Modification-dependent Protein Catabolic Process Regulation Of Proteolysis Post-translational Protein Modification Protein Neddylation	Negative Regulation Of Protein Ubiquitination Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Cellular Response To UV
Pathways		TGF-beta receptor signaling activates SMADs UCH proteinases Cargo recognition for clathrin-mediated endocytosis Neddylation Iron uptake and transport
Drugs
Diseases
GWAS		Mean corpuscular volume ( 29403010) Systolic blood pressure (cigarette smoking interaction) ( 26752167)	Eosinophil counts ( 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 27863252) Neutrophil percentage of granulocytes ( 27863252) Social autistic-like traits ( 24133439) Sum eosinophil basophil counts ( 27863252)
Interacting Genes		42 interacting genes: AHR ARIH2 ATE1 ATXN3 CBLB CDC34 COPS5 COPS6 CTRC CUL1 CUL2 CUL3 CUL4B DNMT3B GARS1 GHR HGS HIF1A N4BP1 NAE1 NUB1 OTUB1 OTUD5 PARP1 POLI PSMA6 PSMD4 PTK2 RAD23A SENP8 SMURF1 TP53 UBA2 UBA3 UBE2K UBE2M UBL7 UBQLN1 UBXN7 UCHL1 UCHL3 YAF2	6 interacting genes: AZI2 CDK6 ITCH LSM1 NEDD8 UBC
Entrez ID		4738	9683
HPRD ID		04412
Ensembl ID		ENSG00000129559	ENSG00000102921
Uniprot IDs		Q15843	O75113
PDB IDs		1NDD 1R4M 1R4N 1XT9 2BKR 2KO3 2N7K 2NVU 3DBH 3DBL 3DBR 3DQV 3GZN 4F8C 4FBJ 4HCP 4P5O 6R7F
Enriched GO Terms of Interacting Partners?
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