NEDD8 and UBXN7

Number of citations of the paper that reports this interaction (PubMedID 22466964)
41

Data Source:
BioGRID (affinity chromatography technology, pull down)

		NEDD8	UBXN7
Description		NEDD8 ubiquitin like modifier	UBX domain protein 7
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GO Annotations	Cellular Component	Cell Nucleus Nucleoplasm Cytoplasm Cytosol Extracellular Exosome	Nucleoplasm Cytosol Nuclear Body VCP-NPL4-UFD1 AAA ATPase Complex
	Molecular Function	Protein Binding Protein Tag Ubiquitin Protein Ligase Binding	Protein Binding Transcription Factor Binding Ubiquitin Protein Ligase Binding Ubiquitin Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Cellular Protein Modification Process Proteolysis Ubiquitin-dependent Protein Catabolic Process Cellular Iron Ion Homeostasis Protein Localization Anatomical Structure Morphogenesis Response To Organic Cyclic Compound Protein Ubiquitination Protein Deubiquitination Modification-dependent Protein Catabolic Process Regulation Of Proteolysis Post-translational Protein Modification Protein Neddylation	Post-translational Protein Modification
Pathways		TGF-beta receptor signaling activates SMADs UCH proteinases Cargo recognition for clathrin-mediated endocytosis Neddylation Iron uptake and transport	Neddylation
Drugs
Diseases
GWAS		Mean corpuscular volume ( 29403010) Systolic blood pressure (cigarette smoking interaction) ( 26752167)	IgM levels ( 28628107)
Interacting Genes		42 interacting genes: AHR ARIH2 ATE1 ATXN3 CBLB CDC34 COPS5 COPS6 CTRC CUL1 CUL2 CUL3 CUL4B DNMT3B GARS1 GHR HGS HIF1A N4BP1 NAE1 NUB1 OTUB1 OTUD5 PARP1 POLI PSMA6 PSMD4 PTK2 RAD23A SENP8 SMURF1 TP53 UBA2 UBA3 UBE2K UBE2M UBL7 UBQLN1 UBXN7 UCHL1 UCHL3 YAF2	6 interacting genes: APP ATP13A3 MAP3K1 NEDD8 SMURF1 VCP
Entrez ID		4738	26043
HPRD ID		04412	19396
Ensembl ID		ENSG00000129559	ENSG00000163960
Uniprot IDs		Q15843	O94888
PDB IDs		1NDD 1R4M 1R4N 1XT9 2BKR 2KO3 2N7K 2NVU 3DBH 3DBL 3DBR 3DQV 3GZN 4F8C 4FBJ 4HCP 4P5O 6R7F	1WJ4 2DAL 2DLX 5X3P 5X4L
Enriched GO Terms of Interacting Partners?
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