ATF1 and CAMK1

Number of citations of the paper that reports this interaction (PubMedID 8384217)
28

Data Source:
HPRD (in vitro)

		ATF1	CAMK1
Description		activating transcription factor 1	calcium/calmodulin dependent protein kinase I
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Transcription Factor Complex ATF1-ATF4 Transcription Factor Complex	Intracellular Nucleus Cytosol Postsynaptic Density Glutamatergic Synapse
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Identical Protein Binding Protein-containing Complex Binding Protein Heterodimerization Activity	Protein Serine/threonine Kinase Activity Calmodulin-dependent Protein Kinase Activity Protein Binding Calmodulin Binding ATP Binding
	Biological Process	Positive Regulation Of Neuron Projection Development Response To Organic Cyclic Compound Response To Cobalt Ion Cellular Protein-containing Complex Assembly Positive Regulation Of DNA Replication Positive Regulation Of Transcription By RNA Polymerase II	Protein Phosphorylation Nucleocytoplasmic Transport Cell Cycle Signal Transduction Positive Regulation Of Neuron Projection Development Negative Regulation Of Protein Binding Regulation Of Protein Localization Positive Regulation Of Peptidyl-serine Phosphorylation Regulation Of Protein Binding Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Protein Export From Nucleus Regulation Of Muscle Cell Differentiation Positive Regulation Of Muscle Cell Differentiation Positive Regulation Of Synapse Structural Plasticity Positive Regulation Of Syncytium Formation By Plasma Membrane Fusion Positive Regulation Of Dendritic Spine Development Positive Regulation Of Protein Serine/threonine Kinase Activity Positive Regulation Of Protein Acetylation Regulation Of Histone H3-K9 Acetylation
Pathways		CREB phosphorylation NGF-stimulated transcription NGF-stimulated transcription	Negative regulation of NMDA receptor-mediated neuronal transmission Activation of RAC1 downstream of NMDARs Activation of RAC1 downstream of NMDARs
Drugs		Pseudoephedrine
Diseases		Clear cell sarcoma of soft tissue
GWAS		Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Colorectal cancer ( 25990418 20972440 24737748) Colorectal cancer or advanced adenoma ( 30510241) Estimated glomerular filtration rate ( 31152163) Male-pattern baldness ( 27182965) Mean arterial pressure ( 27618448) Multiple sclerosis ( 31604244) Sudden cardiac arrest ( 21658281) Systolic blood pressure ( 30578418)
Interacting Genes		23 interacting genes: BRCA1 CAMK1 CAMK2A CAMK2G CREB1 CREBBP CREM CSNK2A1 CSNK2A2 CSNK2B DNMT3L EDF1 GABPA GABPB1 HNF1B JUN MAPKAPK2 MAPKAPK3 PRKACA RPS6KA4 RPS6KA5 SPI1 SRA1	20 interacting genes: APP ATF1 CALM1 CAMKK1 CAMKK2 CCND1 CDK4 CDKN1B EIF4G3 FBXO7 GAPDH GCM1 HDAC5 HSPB1 MARK2 NOS1 PIK3R3 PPME1 PPP2CA SYN1
Entrez ID		466	8536
HPRD ID		00440	05412
Ensembl ID		ENSG00000123268	ENSG00000134072
Uniprot IDs		P18846	B0YIY3 Q14012
PDB IDs			4FG7 4FG8 4FG9 4FGB
Enriched GO Terms of Interacting Partners?
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