CAMK1 and EIF4G3

Number of citations of the paper that reports this interaction (PubMedID 14507913)
12

Data Source:
HPRD (in vivo, in vitro)

		CAMK1	EIF4G3
Description		calcium/calmodulin dependent protein kinase I	eukaryotic translation initiation factor 4 gamma 3
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GO Annotations	Cellular Component	Intracellular Nucleus Cytosol Postsynaptic Density Glutamatergic Synapse	Cytosol Eukaryotic Translation Initiation Factor 4F Complex
	Molecular Function	Protein Serine/threonine Kinase Activity Calmodulin-dependent Protein Kinase Activity Protein Binding Calmodulin Binding ATP Binding	RNA Cap Binding RNA Binding MRNA Binding Translation Initiation Factor Activity Translation Factor Activity, RNA Binding
	Biological Process	Protein Phosphorylation Nucleocytoplasmic Transport Cell Cycle Signal Transduction Positive Regulation Of Neuron Projection Development Negative Regulation Of Protein Binding Regulation Of Protein Localization Positive Regulation Of Peptidyl-serine Phosphorylation Regulation Of Protein Binding Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Protein Export From Nucleus Regulation Of Muscle Cell Differentiation Positive Regulation Of Muscle Cell Differentiation Positive Regulation Of Synapse Structural Plasticity Positive Regulation Of Syncytium Formation By Plasma Membrane Fusion Positive Regulation Of Dendritic Spine Development Positive Regulation Of Protein Serine/threonine Kinase Activity Positive Regulation Of Protein Acetylation Regulation Of Histone H3-K9 Acetylation	Translational Initiation Regulation Of Translational Initiation Negative Regulation Of Autophagy
Pathways		Negative regulation of NMDA receptor-mediated neuronal transmission Activation of RAC1 downstream of NMDARs Activation of RAC1 downstream of NMDARs	ISG15 antiviral mechanism
Drugs
Diseases
GWAS			Chronotype ( 30696823) Cognitive decline rate in late mild cognitive impairment ( 26252872) General risk tolerance (MTAG) ( 30643258) Morning person ( 30696823) Postoperative acute renal failure after cardiac surgery ( 30678657) Social science traits (pleiotropy) (HIPO component 1) ( 30289880) Superior frontal gyrus grey matter volume ( 25335168)
Interacting Genes		20 interacting genes: APP ATF1 CALM1 CAMKK1 CAMKK2 CCND1 CDK4 CDKN1B EIF4G3 FBXO7 GAPDH GCM1 HDAC5 HSPB1 MARK2 NOS1 PIK3R3 PPME1 PPP2CA SYN1	8 interacting genes: CAMK1 EIF4A1 EIF4E HSPB1 LIG4 MKNK1 PABPC1 VAV2
Entrez ID		8536	8672
HPRD ID		05412	06802
Ensembl ID		ENSG00000134072	ENSG00000075151
Uniprot IDs		B0YIY3 Q14012	A0A0A0MSA7 O43432 Q59GJ0
PDB IDs		4FG7 4FG8 4FG9 4FGB	1HU3
Enriched GO Terms of Interacting Partners?
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