ATF1 and HNF1B

Number of citations of the paper that reports this interaction (PubMedID 9671480)
2

Data Source:
HPRD (in vitro)

		ATF1	HNF1B
Description		activating transcription factor 1	HNF1 homeobox B
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Transcription Factor Complex ATF1-ATF4 Transcription Factor Complex	Nuclear Chromatin Nucleus Nucleoplasm Transcription Factor Complex Intracellular Membrane-bounded Organelle
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Identical Protein Binding Protein-containing Complex Binding Protein Heterodimerization Activity	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Identical Protein Binding Protein-containing Complex Binding
	Biological Process	Positive Regulation Of Neuron Projection Development Response To Organic Cyclic Compound Response To Cobalt Ion Cellular Protein-containing Complex Assembly Positive Regulation Of DNA Replication Positive Regulation Of Transcription By RNA Polymerase II	Negative Regulation Of Transcription By RNA Polymerase II Endodermal Cell Fate Specification Kidney Development Inner Cell Mass Cell Differentiation Regulation Of Transcription By RNA Polymerase II Notch Signaling Pathway Response To Glucose Anterior/posterior Pattern Specification Response To Organic Cyclic Compound Insulin Secretion Regulation Of Wnt Signaling Pathway Hindbrain Development Pancreas Development Circadian Regulation Of Gene Expression Regulation Of Pronephros Size Pronephric Nephron Tubule Development Response To Drug Positive Regulation Of Transcription, DNA-templated Embryonic Digestive Tract Morphogenesis Branching Morphogenesis Of An Epithelial Tube Pronephros Development Epithelial Cell Proliferation Positive Regulation Of Transcription Initiation From RNA Polymerase II Promoter Ureteric Bud Elongation Hepatoblast Differentiation Negative Regulation Of Mesenchymal Cell Apoptotic Process Involved In Mesonephric Nephron Morphogenesis Protein-DNA Complex Assembly Hepatocyte Differentiation Regulation Of Branch Elongation Involved In Ureteric Bud Branching Mesonephric Duct Formation Negative Regulation Of Mesenchymal Cell Apoptotic Process Involved In Metanephros Development
Pathways		CREB phosphorylation NGF-stimulated transcription NGF-stimulated transcription	Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells Regulation of gene expression in early pancreatic precursor cells
Drugs		Pseudoephedrine
Diseases		Clear cell sarcoma of soft tissue	Maturity onset diabetes of the young (MODY) Type II diabetes mellitus Uromodulin-associated kidney diseases, including: Medullary cystic kidney disease 2; Familial juvenile hyperuremic nephropathy; Glomerulocystic kidney disease
GWAS		Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Colorectal cancer ( 25990418 20972440 24737748) Colorectal cancer or advanced adenoma ( 30510241) Estimated glomerular filtration rate ( 31152163) Male-pattern baldness ( 27182965) Mean arterial pressure ( 27618448) Multiple sclerosis ( 31604244) Sudden cardiac arrest ( 21658281) Systolic blood pressure ( 30578418)	Benign prostatic hyperplasia and lower urinary tract symptoms ( 30410027) Blood urea nitrogen levels ( 31152163 29403010) Body mass index ( 28892062) Cancer ( 27197191) Cancer (pleiotropy) ( 27197191) Endometrial cancer ( 30093612 27008869 21499250 27135401) Endometrial cancer (endometrioid histology) ( 30093612) Endometrial endometrioid carcinoma ( 27135401) Epithelial ovarian cancer ( 25581431) Frontotemporal dementia ( 26154020) Gallstone disease ( 30504769) Medication use (drugs used in diabetes) ( 31015401) Neuritic plaque ( 25188341) Ovarian cancer ( 23535730) Pancreatic cancer ( 29422604) Pancreatic ductal adenocarcinoma ( 30541042) Prostate cancer ( 20676098 18264096 18264097 30410027 31562322 25939597 26443449 27262462) Prostate-specific antigen levels ( 30410027 28139693) Serum prostate-specific antigen levels ( 21160077) Testicular germ cell tumor ( 25877299 28604728 28604732) Type 2 diabetes ( 22885922 24509480 30054458 30297969 26818947 23945395 22961080 20581827 30718926 28869590)
Interacting Genes		23 interacting genes: BRCA1 CAMK1 CAMK2A CAMK2G CREB1 CREBBP CREM CSNK2A1 CSNK2A2 CSNK2B DNMT3L EDF1 GABPA GABPB1 HNF1B JUN MAPKAPK2 MAPKAPK3 PRKACA RPS6KA4 RPS6KA5 SPI1 SRA1	5 interacting genes: ATF1 CREB1 CREBBP H3C1 HNF1A
Entrez ID		466	6928
HPRD ID		00440	08926
Ensembl ID		ENSG00000123268	ENSG00000275410
Uniprot IDs		P18846	A0A087WZC2 A0A0C4DGS8 E0YMJ6 P35680 Q6FHW6
PDB IDs			2DA6 2H8R 5K9S
Enriched GO Terms of Interacting Partners?
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