MSX1 and NMNAT1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		MSX1	NMNAT1
Description		msh homeobox 1	nicotinamide nucleotide adenylyltransferase 1
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm	Nucleus Nucleoplasm Cytoplasm Nuclear Body
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific P53 Binding Enhancer Binding	Nicotinamide-nucleotide Adenylyltransferase Activity Nicotinate-nucleotide Adenylyltransferase Activity Protein Binding ATP Binding Identical Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Cell Morphogenesis In Utero Embryonic Development Epithelial To Mesenchymal Transition Involved In Endocardial Cushion Formation Muscle Organ Development Negative Regulation Of Cell Proliferation Anterior/posterior Pattern Specification Mesenchymal Cell Proliferation Pituitary Gland Development Signal Transduction Involved In Regulation Of Gene Expression Negative Regulation Of Cell Growth Positive Regulation Of BMP Signaling Pathway Midbrain Development Protein Localization To Nucleus Embryonic Forelimb Morphogenesis Embryonic Hindlimb Morphogenesis Embryonic Nail Plate Morphogenesis Middle Ear Morphogenesis Odontogenesis Of Dentin-containing Tooth Regulation Of Odontogenesis Negative Regulation Of Apoptotic Process Positive Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Positive Regulation Of Transcription By RNA Polymerase II Embryonic Morphogenesis Stem Cell Differentiation Protein Stabilization Negative Regulation Of Striated Muscle Cell Differentiation Roof Of Mouth Development Face Morphogenesis Bone Morphogenesis Cartilage Morphogenesis Mammary Gland Epithelium Development BMP Signaling Pathway Involved In Heart Development Cellular Response To Nicotine Activation Of Meiosis Positive Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Negative Regulation Of Transcription Regulatory Region DNA Binding Positive Regulation Of Mesenchymal Cell Apoptotic Process	Nucleotide Biosynthetic Process NAD Biosynthetic Process Response To Wounding NAD Metabolic Process Positive Regulation Of MAPK Cascade Negative Regulation Of Neuron Apoptotic Process Negative Regulation Of Apoptotic DNA Fragmentation ATP Generation From Poly-ADP-D-ribose
Pathways			Nicotinate metabolism
Drugs			Nicotinamide Mononucleotide Deamido-Nad+
Diseases		Isolated orofacial clefts, including: Cleft lip with or without cleft palate; Cleft palate Tooth agenesis; Hypodontia Tooth and nail syndrome; Witkop syndrome
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406) Breast cancer and/or colorectal cancer ( 29698419) Congenital heart disease ( 23708191) Electrocardiographic conduction measures ( 19389651) Nonsyndromic cleft lip with cleft palate ( 28232668)	Resting heart rate ( 27798624)
Interacting Genes		24 interacting genes: CREBBP DLX2 DLX5 HOXC8 ING4 LHX2 MED19 MSX2 NMNAT1 PAX3 PAX9 PIAS1 POU2F1 RGS7 SP1 SUMO1 SUMO2 TAF1 TBP TLE1 TLE2 TLE4 TLE5 TP53	12 interacting genes: APP BANP CCNC FLOT2 KPNA2 MSX1 NEK3 NTRK2 PABPC4 SIK1 SIRT1 TDO2
Entrez ID		4487	64802
HPRD ID		00866	16369
Ensembl ID		ENSG00000163132	ENSG00000173614
Uniprot IDs		P28360	A0A024R4E1 B1AN62 Q9HAN9
PDB IDs			1GZU 1KKU 1KQN 1KQO 1KR2
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?