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ASPA and ZYG11B

ASPA

ZYG11B

Description aspartoacylase zyg-11 family member B, cell cycle regulator
Image No pdb structure
GO Annotations Cellular Component
  • Nucleus
  • Cytosol
  • Cul2-RING Ubiquitin Ligase Complex
Molecular Function
  • Aminoacylase Activity
  • Protein Binding
  • Hydrolase Activity, Acting On Ester Bonds
  • Hydrolase Activity, Acting On Carbon-nitrogen (but Not Peptide) Bonds, In Linear Amides
  • Aspartoacylase Activity
  • Identical Protein Binding
  • Metal Ion Binding
Biological Process
  • Aspartate Catabolic Process
  • Cellular Amino Acid Biosynthetic Process
  • Central Nervous System Myelination
  • Positive Regulation Of Oligodendrocyte Differentiation
  • Protein Quality Control For Misfolded Or Incompletely Synthesized Proteins
  • Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Pathways
  • Aspartate and asparagine metabolism
Drugs
  • L-Aspartic Acid
  • Zinc
Diseases
  • Canavan disease (CD)
GWAS
  • Myopia (pathological) ( 23049088)
Interacting Genes 2 interacting genes: ACY3 ZYG11B 13 interacting genes: ARPC2 ASPA BTBD2 BTF3L4 CFL2 CUL2 ELOB ELOC NDC1 OSBPL9 SH2D2A TLR6 UCK2
Entrez ID 443 79699
HPRD ID 02033 13356
Ensembl ID ENSG00000108381 ENSG00000162378
Uniprot IDs P45381 Q6FH48 A8DPD7 B4DK95 Q9C0D3
PDB IDs 2I3C 2O4H 2O53 2Q51 4MRI 4MXU 4NFR 4TNU
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?

© Madhavi K. Ganapathiraju 2012-2025

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