SEC61A1

Description		SEC61 translocon subunit alpha 1
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Sec61 Translocon Complex Endoplasmic Reticulum Membrane Cytosol Membrane Integral Component Of Endoplasmic Reticulum Membrane
	Molecular Function	Signal Sequence Binding Calcium Channel Activity Protein Binding Protein Transmembrane Transporter Activity Ribosome Binding
	Biological Process	Cotranslational Protein Targeting To Membrane SRP-dependent Cotranslational Protein Targeting To Membrane SRP-dependent Cotranslational Protein Targeting To Membrane, Translocation Posttranslational Protein Targeting To Endoplasmic Reticulum Membrane Endoplasmic Reticulum Organization Posttranslational Protein Targeting To Membrane, Translocation Response To Interferon-gamma Pronephric Nephron Development Protein Targeting To ER Calcium Ion Transmembrane Transport
Pathways		ER-Phagosome pathway SRP-dependent cotranslational protein targeting to membrane
Drugs
Diseases
GWAS		Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143) Gestational age at birth (maternal effect) ( 28877031)
Interacting Genes		9 interacting genes: ACAD9 BAG6 CALM1 GET3 HSPA5 MLH1 SEC61G SERP1 TNF
Entrez ID		29927
HPRD ID		15316
Ensembl ID		ENSG00000058262
Uniprot IDs		B3KME8 B3KNF6 P61619
PDB IDs
Enriched GO Terms of Interacting Partners?
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