MICB and KLRC4

Number of citations of the paper that reports this interaction (PubMedID 12133964)
12

Data Source:
HPRD (in vitro)

		MICB	KLRC4
Description		MHC class I polypeptide-related sequence B	killer cell lectin like receptor C4
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Plasma Membrane External Side Of Plasma Membrane Cell Surface Integral Component Of Membrane	Integral Component Of Membrane
	Molecular Function	Natural Killer Cell Lectin-like Receptor Binding
	Biological Process	Positive Regulation Of T Cell Mediated Cytotoxicity Adaptive Immune Response Immune Response-activating Cell Surface Receptor Signaling Pathway Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class Ib Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Via ER Pathway, TAP-independent Immune Response Response To Oxidative Stress Response To Heat Viral Process Cytolysis Response To Retinoic Acid Gamma-delta T Cell Activation Negative Regulation Of Defense Response To Virus By Host Regulation Of Immune Response
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Diseases
GWAS		AIDS progression ( 19115949) Alcohol use disorder ( 30940813) Allergic sensitization ( 23817571) Arterial stiffness index ( 31235810) Asthma ( 31619474 29273806) Asthma (childhood onset) ( 31619474 29273806) Asthma and major depressive disorder ( 31619474) Atopic dermatitis ( 26482879) Autism spectrum disorder or schizophrenia ( 28540026) Behcet's disease ( 23001997) Blood protein levels ( 30072576 29875488 28240269) Cervical cancer ( 28806749) Cold sores ( 28928442) Crohn's disease ( 23128233) Cutaneous lupus erythematosus ( 25827949) Dengue shock syndrome ( 22001756) Handedness (non-right-handed vs right-handed) ( 31504236) Hodgkin's lymphoma ( 22286212) Inflammatory bowel disease ( 28067908) Metabolic syndrome ( 22399527) Midgestational circulating levels of PBDEs ( 28235828) Monocyte count ( 27863252) Mononucleosis ( 28928442) Myositis ( 26291516) Oral cavity cancer ( 27749845) Parental longevity (combined parental attained age, Martingale residuals) ( 29227965) Parental longevity (father's attained age) ( 29227965) Plateletcrit ( 27863252) Pneumonia ( 28928442) Psychosis (atypical) ( 24132900) Pulmonary function ( 21946350) Rosacea symptom severity ( 29771307) Sarcoidosis (non-Lofgren's syndrome without extrapulmonary manifestations) ( 26651848) Serum metabolite levels ( 31636271) Serum metabolite levels (CMS) ( 31636271) Ulcerative colitis ( 28067908)	Behcet's disease ( 23291587) Blood protein levels ( 28240269) Psoriasis ( 28537254)
Interacting Genes		2 interacting genes: KLRC4 KLRK1	4 interacting genes: MICB RAE1 TYROBP ULBP1
Entrez ID		4277	8302
HPRD ID		03894	16008
Ensembl ID		ENSG00000204516	ENSG00000183542
Uniprot IDs		A0A0G2JHB5 B4DUT9 B7Z8M1 F5H7Q8 Q29980 X6R344	O43908
PDB IDs		1JE6 2WY3
Enriched GO Terms of Interacting Partners?
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