MICB

Description		MHC class I polypeptide-related sequence B
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GO Annotations	Cellular Component	Extracellular Space Plasma Membrane External Side Of Plasma Membrane Cell Surface Integral Component Of Membrane
	Molecular Function	Natural Killer Cell Lectin-like Receptor Binding
	Biological Process	Positive Regulation Of T Cell Mediated Cytotoxicity Adaptive Immune Response Immune Response-activating Cell Surface Receptor Signaling Pathway Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class Ib Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Via ER Pathway, TAP-independent Immune Response Response To Oxidative Stress Response To Heat Viral Process Cytolysis Response To Retinoic Acid Gamma-delta T Cell Activation Negative Regulation Of Defense Response To Virus By Host Regulation Of Immune Response
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Diseases
GWAS		AIDS progression ( 19115949) Alcohol use disorder ( 30940813) Allergic sensitization ( 23817571) Arterial stiffness index ( 31235810) Asthma ( 31619474 29273806) Asthma (childhood onset) ( 31619474 29273806) Asthma and major depressive disorder ( 31619474) Atopic dermatitis ( 26482879) Autism spectrum disorder or schizophrenia ( 28540026) Behcet's disease ( 23001997) Blood protein levels ( 30072576 29875488 28240269) Cervical cancer ( 28806749) Cold sores ( 28928442) Crohn's disease ( 23128233) Cutaneous lupus erythematosus ( 25827949) Dengue shock syndrome ( 22001756) Handedness (non-right-handed vs right-handed) ( 31504236) Hodgkin's lymphoma ( 22286212) Inflammatory bowel disease ( 28067908) Metabolic syndrome ( 22399527) Midgestational circulating levels of PBDEs ( 28235828) Monocyte count ( 27863252) Mononucleosis ( 28928442) Myositis ( 26291516) Oral cavity cancer ( 27749845) Parental longevity (combined parental attained age, Martingale residuals) ( 29227965) Parental longevity (father's attained age) ( 29227965) Plateletcrit ( 27863252) Pneumonia ( 28928442) Psychosis (atypical) ( 24132900) Pulmonary function ( 21946350) Rosacea symptom severity ( 29771307) Sarcoidosis (non-Lofgren's syndrome without extrapulmonary manifestations) ( 26651848) Serum metabolite levels ( 31636271) Serum metabolite levels (CMS) ( 31636271) Ulcerative colitis ( 28067908)
Interacting Genes		2 interacting genes: KLRC4 KLRK1
Entrez ID		4277
HPRD ID		03894
Ensembl ID		ENSG00000204516
Uniprot IDs		A0A0G2JHB5 B4DUT9 B7Z8M1 F5H7Q8 Q29980 X6R344
PDB IDs		1JE6 2WY3
Enriched GO Terms of Interacting Partners?
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