GSTK1 and PEX5

Number of citations of the paper that reports this interaction (PubMedID 20178365)
16

Data Source:
BioGRID (affinity chromatography technology, unspecified method, affinity chromatography technology)

		GSTK1	PEX5
Description		glutathione S-transferase kappa 1	peroxisomal biogenesis factor 5
Image
GO Annotations	Cellular Component	Intracellular Mitochondrion Mitochondrial Matrix Peroxisome Peroxisomal Matrix Cytosol Membrane Extracellular Exosome	Cytoplasm Peroxisome Peroxisomal Membrane Golgi Apparatus Cytosol Membrane Protein-containing Complex
	Molecular Function	Glutathione Transferase Activity Glutathione Peroxidase Activity Protein Binding Protein Disulfide Oxidoreductase Activity	Peroxisome Targeting Sequence Binding Peroxisome Matrix Targeting Signal-1 Binding Protein Binding Enzyme Binding Small GTPase Binding Peroxisome Membrane Targeting Sequence Binding Protein N-terminus Binding
	Biological Process	Protein Targeting To Peroxisome Glutathione Metabolic Process Epithelial Cell Differentiation Oxidation-reduction Process Cellular Oxidant Detoxification Glutathione Derivative Biosynthetic Process	Protein Targeting To Peroxisome Protein Import Into Peroxisome Matrix Protein Import Into Peroxisome Matrix, Docking Protein Ubiquitination Negative Regulation Of Protein Complex Assembly Protein Import Into Peroxisome Membrane
Pathways		Glutathione conjugation Peroxisomal protein import Peroxisomal protein import	Pexophagy
Drugs		Glutathione GLUTATHIONE SULFINATE
Diseases			Zellweger syndrome spectrum, including: Zellweger syndrome (ZS); Adrenoleukodystrophy, neonatal (NALD); Infantile Refsum disease (IRD)
GWAS			IgG glycosylation ( 23382691) Night sleep phenotypes ( 27126917)
Interacting Genes		6 interacting genes: CCNDBP1 FAM9B GRB2 PEX5 PIP4K2A PRPF19	71 interacting genes: ACD ACOT2 ACOT4 ACOT8 ACOX2 ACOX3 AGXT AMACR ANKRD50 ATM BAAT BRCA1 CAPRIN2 CCDC14 CROT DAO DDO DECR2 DHRS4 ECI2 EP400P1 EPHX2 FIS1 GDPD5 GNPAT GSTK1 HACL1 HAO1 HAO2 HMGCL HOXA7 HSPA1A IDE IDH1 LDHB LONP2 MKRN3 MLYCD MPV17 NOS2 NUDT19 NUDT3 NUDT7 PAOX PDZK1 PEX1 PEX10 PEX12 PEX13 PEX14 PEX26 PEX6 PEX7 PIPOX POT1 PRDX5 PRR13 RPL14 S100A6 SCARB1 SCP2 SIRT3 SLC27A2 SNUPN SSTR5 TINF2 TM6SF1 TOMM7 USP2 USP9X ZNF772
Entrez ID		373156	5830
HPRD ID		13613	02684
Ensembl ID		ENSG00000197448	ENSG00000139197
Uniprot IDs		Q6FII1 Q9Y2Q3	A0A0S2Z480 A0A0S2Z4F3 A0A0S2Z4H1 B4DR50 B4E0T2 P50542
PDB IDs		1YZX 3RPN 3RPP	1FCH 2C0L 2C0M 2J9Q 2W84 3R9A 4BXU 4KXK 4KYO
Enriched GO Terms of Interacting Partners?
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