GSTK1 and PRPF19

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		GSTK1	PRPF19
Description		glutathione S-transferase kappa 1	pre-mRNA processing factor 19
Image
GO Annotations	Cellular Component	Intracellular Mitochondrion Mitochondrial Matrix Peroxisome Peroxisomal Matrix Cytosol Membrane Extracellular Exosome	Prp19 Complex Nucleus Nucleoplasm DNA Replication Factor A Complex Cytoplasm Lipid Droplet Spindle Membrane Nuclear Speck Site Of Double-strand Break U2-type Catalytic Step 1 Spliceosome U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome
	Molecular Function	Glutathione Transferase Activity Glutathione Peroxidase Activity Protein Binding Protein Disulfide Oxidoreductase Activity	Ubiquitin-protein Transferase Activity Protein Binding Ubiquitin-ubiquitin Ligase Activity Identical Protein Binding Ubiquitin Protein Ligase Activity
	Biological Process	Protein Targeting To Peroxisome Glutathione Metabolic Process Epithelial Cell Differentiation Oxidation-reduction Process Cellular Oxidant Detoxification Glutathione Derivative Biosynthetic Process	Protein Polyubiquitination Spliceosomal Tri-snRNP Complex Assembly Spliceosomal Complex Assembly Generation Of Catalytic Spliceosome For First Transesterification Step MRNA Splicing, Via Spliceosome Inner Cell Mass Cell Proliferation Transcription-coupled Nucleotide-excision Repair Double-strand Break Repair Via Nonhomologous End Joining Lipid Biosynthetic Process Proteasomal Protein Catabolic Process Cellular Protein Localization Positive Regulation Of Neuron Differentiation Positive Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of Astrocyte Differentiation Protein K63-linked Ubiquitination Signal Transduction Involved In DNA Damage Checkpoint
Pathways		Glutathione conjugation Peroxisomal protein import Peroxisomal protein import	Formation of TC-NER Pre-Incision Complex Transcription-Coupled Nucleotide Excision Repair (TC-NER) Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER mRNA Splicing - Major Pathway
Drugs		Glutathione GLUTATHIONE SULFINATE
Diseases
GWAS
Interacting Genes		6 interacting genes: CCNDBP1 FAM9B GRB2 PEX5 PIP4K2A PRPF19	14 interacting genes: DDX42 DNTT EGLN3 ESR1 EXOC7 GSTK1 HSPB1 POLR2A PRCC PRPF8 PSMB4 RPA3 U2AF1 UBE2D3
Entrez ID		373156	27339
HPRD ID		13613	12214
Ensembl ID		ENSG00000197448	ENSG00000110107
Uniprot IDs		Q6FII1 Q9Y2Q3	Q9UMS4
PDB IDs		1YZX 3RPN 3RPP	4LG8 5MQF 5XJC 5YZG 5Z56 5Z57 6FF7 6ICZ 6ID0 6ID1 6QDV
Enriched GO Terms of Interacting Partners?
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