AQP2 and UBE2J1

Number of citations of the paper that reports this interaction (PubMedID 28931009)
7

Data Source:
BioGRID (two hybrid)

		AQP2	UBE2J1
Description		aquaporin 2	ubiquitin conjugating enzyme E2 J1
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Plasma Membrane Integral Component Of Plasma Membrane Membrane Integral Component Of Membrane Basolateral Plasma Membrane Apical Plasma Membrane Transport Vesicle Membrane Recycling Endosome Extracellular Exosome Lumenal Side Of Membrane	Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Water Transmembrane Transporter Activity Protein Binding Glycerol Transmembrane Transporter Activity Water Channel Activity	ATP Binding Ubiquitin Protein Ligase Binding Ubiquitin Conjugating Enzyme Activity
	Biological Process	Renal Water Homeostasis Renal Water Transport Water Transport Glycerol Transport Cellular Response To Water Deprivation Protein Homotetramerization Transmembrane Transport Cellular Response To Copper Ion Cellular Response To Mercury Ion Metanephric Collecting Duct Development	Spermatid Development Protein Ubiquitination Protein N-linked Glycosylation Via Asparagine Ubiquitin-dependent ERAD Pathway Regulation Of Tumor Necrosis Factor Biosynthetic Process Negative Regulation Of Retrograde Protein Transport, ER To Cytosol
Pathways		Vasopressin regulates renal water homeostasis via Aquaporins Passive transport by Aquaporins	Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases		Congenital nephrogenic diabetes insipidus (NDI)
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406) Allergic rhinitis ( 30013184) Obsessive-compulsive disorder ( 22889921)
Interacting Genes		25 interacting genes: ACTB BCAP31 C4orf3 CCDC167 CERT1 CLDN7 CREB3 EEF1A1 ELL2 ERG28 GPAA1 IER3 NDFIP2 PLP2 SLC5A2 SNX5 SPCS1 SSR3 STUB1 STX8 SUPT20H TM9SF2 TMEM230 UBE2J1 VAPB	14 interacting genes: AQP2 BIRC2 BRCA1 CREB3 DIO2 LRSAM1 MAPKAPK2 PJA2 PRKN RNF2 TOPORS TRIM27 TRIM63 UBA1
Entrez ID		359	51465
HPRD ID		00141	15599
Ensembl ID		ENSG00000167580	ENSG00000198833
Uniprot IDs		P41181	Q9Y385
PDB IDs		4NEF 4OJ2 6QF5
Enriched GO Terms of Interacting Partners?
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