IL10RB and UCN3

Number of citations of the paper that reports this interaction (PubMedID 11416224)
216

Data Source:
HPRD (in vitro)

		IL10RB	UCN3
Description		interleukin 10 receptor subunit beta	urocortin 3
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GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Interleukin-28 Receptor Complex	Extracellular Region Extracellular Space Varicosity Axon Terminus
	Molecular Function	Cytokine Receptor Activity Interleukin-10 Receptor Activity Protein Binding Signaling Receptor Activity	Hormone Activity Corticotropin-releasing Hormone Receptor Binding Corticotropin-releasing Hormone Receptor 2 Binding
	Biological Process	Inflammatory Response Immune Response Signal Transduction Cytokine-mediated Signaling Pathway Positive Regulation Of JAK-STAT Cascade Defense Response To Virus	Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Digestion Response To Glucose Hormone-mediated Signaling Pathway Cellular Response To Nutrient Levels Positive Regulation Of Insulin Secretion Response To Immobilization Stress Response To Starvation Positive Regulation Of Membrane Potential Response To Corticosterone Cellular Response To Hypoxia
Pathways		Other interleukin signaling Interleukin-10 signaling Interleukin-20 family signaling	Class B/2 (Secretin family receptors)
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Crohn's disease ( 23128233) Multiple sclerosis ( 31604244) Narcolepsy ( 24204295 23459209)	Intelligence ( 22449649)
Interacting Genes		7 interacting genes: IFNL2 IFNL3 IL10 IL10RA IL22 UCN2 UCN3	3 interacting genes: CRHR1 CRHR2 IL10RB
Entrez ID		3588	114131
HPRD ID		00473	12066
Ensembl ID		ENSG00000243646	ENSG00000178473
Uniprot IDs		Q08334	Q969E3
PDB IDs		3LQM 5T5W	2RMH 3N93
Enriched GO Terms of Interacting Partners?
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