UCN3 and CRHR2

Number of citations of the paper that reports this interaction (PubMedID 11416224)
216

Data Source:
HPRD (two hybrid, in vitro)

		UCN3	CRHR2
Description		urocortin 3	corticotropin releasing hormone receptor 2
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Varicosity Axon Terminus	Plasma Membrane Integral Component Of Plasma Membrane Axon Dendrite Axon Terminus
	Molecular Function	Hormone Activity Corticotropin-releasing Hormone Receptor Binding Corticotropin-releasing Hormone Receptor 2 Binding	Protein Binding Corticotrophin-releasing Factor Receptor Activity Peptide Hormone Binding Corticotropin-releasing Hormone Receptor Activity
	Biological Process	Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Digestion Response To Glucose Hormone-mediated Signaling Pathway Cellular Response To Nutrient Levels Positive Regulation Of Insulin Secretion Response To Immobilization Stress Response To Starvation Positive Regulation Of Membrane Potential Response To Corticosterone Cellular Response To Hypoxia	Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Hormone-mediated Signaling Pathway Long-term Synaptic Potentiation Cellular Response To Corticotropin-releasing Hormone Stimulus
Pathways		Class B/2 (Secretin family receptors)	G alpha (s) signalling events Synthesis, secretion, and deacylation of Ghrelin ADORA2B mediated anti-inflammatory cytokines production
Drugs
Diseases
GWAS		Intelligence ( 22449649)	Type 2 diabetes ( 24509480 30297969)
Interacting Genes		3 interacting genes: CRHR1 CRHR2 IL10RB	6 interacting genes: APP CRH GCC1 UCN UCN2 UCN3
Entrez ID		114131	1395
HPRD ID		12066	03614
Ensembl ID		ENSG00000178473	ENSG00000106113
Uniprot IDs		Q969E3	A0A090N7T4 Q13324
PDB IDs		2RMH 3N93	3N93 3N95 3N96
Enriched GO Terms of Interacting Partners?
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