IL10RB and IFNL3

Number of citations of the paper that reports this interaction (PubMedID 12469119)
445

		IL10RB	IFNL3
Description		interleukin 10 receptor subunit beta	interferon lambda 3
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GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Interleukin-28 Receptor Complex	Extracellular Region Extracellular Space
	Molecular Function	Cytokine Receptor Activity Interleukin-10 Receptor Activity Protein Binding Signaling Receptor Activity	Signaling Receptor Binding Cytokine Activity
	Biological Process	Inflammatory Response Immune Response Signal Transduction Cytokine-mediated Signaling Pathway Positive Regulation Of JAK-STAT Cascade Defense Response To Virus	JAK-STAT Cascade Cytokine-mediated Signaling Pathway Negative Regulation Of Viral Genome Replication Innate Immune Response Positive Regulation Of Immune Response Defense Response To Virus
Pathways		Other interleukin signaling Interleukin-10 signaling Interleukin-20 family signaling	Interleukin-20 family signaling
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Crohn's disease ( 23128233) Multiple sclerosis ( 31604244) Narcolepsy ( 24204295 23459209)	Hepatitis C (spontaneous viral clearance) ( 30593799) Mucinous ovarian carcinoma ( 26075790)
Interacting Genes		7 interacting genes: IFNL2 IFNL3 IL10 IL10RA IL22 UCN2 UCN3	1 interacting genes: IL10RB
Entrez ID		3588	282617
HPRD ID		00473	09587
Ensembl ID		ENSG00000243646	ENSG00000197110
Uniprot IDs		Q08334	A0A0C4DGW8 Q8IZI9
PDB IDs		3LQM 5T5W	3HHC 5T5W
Enriched GO Terms of Interacting Partners?
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