ID3 and SAP30

Number of citations of the paper that reports this interaction (PubMedID 20211142)
329

Data Source:
BioGRID (two hybrid)

		ID3	SAP30
Description		inhibitor of DNA binding 3, HLH protein	Sin3A associated protein 30
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GO Annotations	Cellular Component	Nucleus	Histone Deacetylase Complex Nucleoplasm
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Protein Domain Specific Binding Protein Dimerization Activity Transcription Regulator Activity Leptomycin B Binding	DNA Binding Transcription Coregulator Activity Transcription Corepressor Activity Histone Deacetylase Activity Protein Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Metanephros Development Regulation Of DNA Replication Multicellular Organism Development Central Nervous System Development Heart Development Muscle Organ Development Response To Wounding Positive Regulation Of Gene Expression Cell Differentiation Epithelial Cell Differentiation Notochord Development Circadian Regulation Of Gene Expression Odontogenesis Positive Regulation Of Apoptotic Process Negative Regulation Of DNA-binding Transcription Factor Activity Negative Regulation Of Myoblast Differentiation Negative Regulation Of Osteoblast Differentiation Negative Regulation Of Transcription, DNA-templated Cellular Response To Leptomycin B Positive Regulation Of Nucleic Acid-templated Transcription	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Histone Deacetylation Skeletal Muscle Cell Differentiation
Pathways		NGF-stimulated transcription	HDACs deacetylate histones NoRC negatively regulates rRNA expression
Drugs
Diseases
GWAS
Interacting Genes		37 interacting genes: ADD1 ATF3 CBFA2T2 CDK2 CEP350 CNOT3 CSK E2F4 ELK1 ELK4 FAM74A1 FHL2 GATA4 GNB2 GTF2A1L HES1 ID4 IFI16 IKBKG MLX MYF5 MYF6 MYOD1 MYOG PAX5 PRDM14 PUF60 RND1 RUNX1T1 SAP30 SREBF1 TCF12 TCF3 TCF4 ZNF3 ZNF408 ZNF626	26 interacting genes: BRMS1 BRMS1L CIR1 CYTOR H2AC16 H2BC21 H3-4 H4-16 HBP1 HDAC1 HDAC2 HTT ID3 ING1 MXD1 NCOR1 NCOR2 PCBD1 RBBP4 RBBP7 RBP1 SAMSN1 SAP30BP SIN3A YY1 ZNF395
Entrez ID		3399	8819
HPRD ID		02608	04540
Ensembl ID		ENSG00000117318	ENSG00000164105
Uniprot IDs		Q02535	O75446
PDB IDs		2LFH	2KDP
Enriched GO Terms of Interacting Partners?
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