ID3 and IFI16

Number of citations of the paper that reports this interaction (PubMedID 11940648)
23

Data Source:
HPRD (in vitro, in vivo)

		ID3	IFI16
Description		inhibitor of DNA binding 3, HLH protein	interferon gamma inducible protein 16
Image
GO Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm Nucleolus Cytosol Membrane Nuclear Speck
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Protein Domain Specific Binding Protein Dimerization Activity Transcription Regulator Activity Leptomycin B Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Double-stranded DNA Binding RNA Binding Protein Binding Transcription Factor Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Metanephros Development Regulation Of DNA Replication Multicellular Organism Development Central Nervous System Development Heart Development Muscle Organ Development Response To Wounding Positive Regulation Of Gene Expression Cell Differentiation Epithelial Cell Differentiation Notochord Development Circadian Regulation Of Gene Expression Odontogenesis Positive Regulation Of Apoptotic Process Negative Regulation Of DNA-binding Transcription Factor Activity Negative Regulation Of Myoblast Differentiation Negative Regulation Of Osteoblast Differentiation Negative Regulation Of Transcription, DNA-templated Cellular Response To Leptomycin B Positive Regulation Of Nucleic Acid-templated Transcription	Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Cytokine Production Activation Of Innate Immune Response Autophagy Inflammatory Response Regulation Of Autophagy Myeloid Cell Differentiation Monocyte Differentiation Positive Regulation Of Type I Interferon Production Positive Regulation Of Interleukin-1 Beta Production Cellular Response To Interferon-beta Regulation Of Gene Expression, Epigenetic Cellular Response To Glucose Starvation Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of DNA Binding Negative Regulation Of Viral Genome Replication Innate Immune Response Negative Regulation Of Innate Immune Response Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Defense Response To Virus Cellular Response To Ionizing Radiation Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Activation Of Cysteine-type Endopeptidase Activity Negative Regulation Of Cysteine-type Endopeptidase Activity
Pathways		NGF-stimulated transcription	STING mediated induction of host immune responses IRF3-mediated induction of type I IFN
Drugs
Diseases
GWAS			Blood protein levels ( 29875488) C-reactive protein ( 22939635) Celiac disease or Rheumatoid arthritis ( 21383967) Neutrophil count in HIV-infection ( 25884002) Obesity-related traits ( 23251661) Periodontal disease-related phenotype (Socransky) ( 26962152)
Interacting Genes		37 interacting genes: ADD1 ATF3 CBFA2T2 CDK2 CEP350 CNOT3 CSK E2F4 ELK1 ELK4 FAM74A1 FHL2 GATA4 GNB2 GTF2A1L HES1 ID4 IFI16 IKBKG MLX MYF5 MYF6 MYOD1 MYOG PAX5 PRDM14 PUF60 RND1 RUNX1T1 SAP30 SREBF1 TCF12 TCF3 TCF4 ZNF3 ZNF408 ZNF626	11 interacting genes: APP AR AURKA BRCA1 CSNK2A1 ID1 ID2 ID3 TP53 TP53BP1 TPR
Entrez ID		3399	3428
HPRD ID		02608	00969
Ensembl ID		ENSG00000117318	ENSG00000163565
Uniprot IDs		Q02535	Q16666
PDB IDs		2LFH	2OQ0 3B6Y 3RLN 3RLO 3RNU 4QGU
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?