SAP30 and BRMS1

Number of citations of the paper that reports this interaction (PubMedID 15451426)
31

Data Source:
HPRD (in vivo)

		SAP30	BRMS1
Description		Sin3A associated protein 30	BRMS1 transcriptional repressor and anoikis regulator
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GO Annotations	Cellular Component	Histone Deacetylase Complex Nucleoplasm	Nucleus Nucleoplasm Cytoplasm Sin3-type Complex
	Molecular Function	DNA Binding Transcription Coregulator Activity Transcription Corepressor Activity Histone Deacetylase Activity Protein Binding Metal Ion Binding	Histone Deacetylase Activity Protein Binding Histone Deacetylase Binding NF-kappaB Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Histone Deacetylation Skeletal Muscle Cell Differentiation	Negative Regulation Of Transcription By RNA Polymerase II Apoptotic Process Histone Deacetylation Negative Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Apoptotic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Protein Deacetylation Positive Regulation Of Anoikis
Pathways		HDACs deacetylate histones NoRC negatively regulates rRNA expression	HDACs deacetylate histones
Drugs
Diseases
GWAS			Bipolar disorder ( 21926972 31043756)
Interacting Genes		26 interacting genes: BRMS1 BRMS1L CIR1 CYTOR H2AC16 H2BC21 H3-4 H4-16 HBP1 HDAC1 HDAC2 HTT ID3 ING1 MXD1 NCOR1 NCOR2 PCBD1 RBBP4 RBBP7 RBP1 SAMSN1 SAP30BP SIN3A YY1 ZNF395	48 interacting genes: ANGPTL4 APP ARID4A BEX2 BRMS1L CEP70 CSNK2A1 CYTOR DIRAS3 DNAJB1 DNAJB6 E2F1 EEF1A1 EP300 GOLGB1 HDAC1 HDAC2 HDAC3 HDAC4 HDAC5 HDAC6 HSP90AA1 HSPA4 IL13RA2 ING1 KLK9 KPNA5 LRIF1 LYPD3 MRC2 NMI PFDN5 PSMC3IP RBBP4 RBBP7 RBP1 RELA SAP30 SIN3A SMARCE1 SMTN SNAI1 SNX6 SPOP SUDS3 TAF1 THRSP UBE2D1
Entrez ID		8819	25855
HPRD ID		04540	05879
Ensembl ID		ENSG00000164105	ENSG00000174744
Uniprot IDs		O75446	G5E9I4 Q9HCU9
PDB IDs		2KDP	2XUS 4AUV
Enriched GO Terms of Interacting Partners?
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