APLP1 and ZNF24

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid, affinity chromatography technology)
HPRD (two hybrid)

		APLP1	ZNF24
Description		amyloid beta precursor like protein 1	zinc finger protein 24
Image
GO Annotations	Cellular Component	Basement Membrane Plasma Membrane Integral Component Of Membrane Perinuclear Region Of Cytoplasm	Nucleus Nucleoplasm
	Molecular Function	Protein Binding Heparin Binding Alpha-2A Adrenergic Receptor Binding Alpha-2B Adrenergic Receptor Binding Alpha-2C Adrenergic Receptor Binding Identical Protein Binding Transition Metal Ion Binding	DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Zinc Ion Binding Identical Protein Binding Sequence-specific DNA Binding
	Biological Process	Endocytosis Apoptotic Process Cell Adhesion Nervous System Development Animal Organ Morphogenesis Cellular Response To Norepinephrine Stimulus Negative Regulation Of Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway	Myelination Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs		Zinc Copper
Diseases
GWAS		Severe influenza A (H1N1) infection ( 26379185)
Interacting Genes		42 interacting genes: ANXA7 APBB1 CDK4 CDKN1A CDKN2C CRCT1 CSNK2B DAB1 DAB2 EEF1A1 EIF2S2 GDF9 GSTM4 HAP1 HLA-DQA1 HSPE1 ING5 KAT5 LRIF1 MPHOSPH6 NACA PCDHA4 PHF10 PIN1 PNP PRNP RAP1B RBM48 RCC1 SAT1 SETDB1 SMN1 SNCA STX5 TCF21 TK1 TMSB4X TOE1 TSC22D1 UTP14A VIM ZNF24	39 interacting genes: APLP1 CCDC130 CEP126 COPS6 CRMP1 DDX6 DZIP3 EEF1A1 EEF1G ERG28 FANCA HAP1 HMGB1 KAT5 LMO2 LRIF1 MID2 MZF1 PPP1CC PRPF31 RBM48 SCAND1 SEC62 SETDB1 TCAF1 TP53 TRIM25 TRIM41 UBE2I UNC119 UTP14A ZBTB16 ZKSCAN8 ZNF165 ZNF174 ZNF446 ZNHIT3 ZSCAN21 ZSCAN32
Entrez ID		333	7572
HPRD ID		00102	01921
Ensembl ID		ENSG00000105290	ENSG00000172466
Uniprot IDs		P51693	P17028
PDB IDs		3PMR 3Q7G 3Q7L 3QMK 4RD9 4RDA	1X6E 3LHR
Enriched GO Terms of Interacting Partners?
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