APLP1 and CRCT1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		APLP1	CRCT1
Description		amyloid beta precursor like protein 1	cysteine rich C-terminal 1
Image			No pdb structure
GO Annotations	Cellular Component	Basement Membrane Plasma Membrane Integral Component Of Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Heparin Binding Alpha-2A Adrenergic Receptor Binding Alpha-2B Adrenergic Receptor Binding Alpha-2C Adrenergic Receptor Binding Identical Protein Binding Transition Metal Ion Binding	Protein Binding
	Biological Process	Endocytosis Apoptotic Process Cell Adhesion Nervous System Development Animal Organ Morphogenesis Cellular Response To Norepinephrine Stimulus Negative Regulation Of Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway
Pathways
Drugs		Zinc Copper
Diseases
GWAS		Severe influenza A (H1N1) infection ( 26379185)	Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 21804549 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Atopic dermatitis ( 26482879) Obesity-related traits ( 23251661) Plantar warts ( 28928442)
Interacting Genes		42 interacting genes: ANXA7 APBB1 CDK4 CDKN1A CDKN2C CRCT1 CSNK2B DAB1 DAB2 EEF1A1 EIF2S2 GDF9 GSTM4 HAP1 HLA-DQA1 HSPE1 ING5 KAT5 LRIF1 MPHOSPH6 NACA PCDHA4 PHF10 PIN1 PNP PRNP RAP1B RBM48 RCC1 SAT1 SETDB1 SMN1 SNCA STX5 TCF21 TK1 TMSB4X TOE1 TSC22D1 UTP14A VIM ZNF24	20 interacting genes: AGTRAP APLP1 CEP126 CHD3 EEF1A1 IGSF21 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP4-12 KRTAP4-2 KRTAP5-9 LRIF1 MEOX2 NOTCH2NLA NUP62 PTN RGS20 TLE1 VIM
Entrez ID		333	54544
HPRD ID		00102	16635
Ensembl ID		ENSG00000105290	ENSG00000169509
Uniprot IDs		P51693	Q9UGL9
PDB IDs		3PMR 3Q7G 3Q7L 3QMK 4RD9 4RDA
Enriched GO Terms of Interacting Partners?
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