APBA1 and LIN7B

Number of citations of the paper that reports this interaction (PubMedID 9753324)
140

Data Source:
HPRD (in vivo)

		APBA1	LIN7B
Description		amyloid beta precursor protein binding family A member 1	lin-7 homolog B, crumbs cell polarity complex component
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GO Annotations	Cellular Component	Nucleus Cytoplasm Golgi Apparatus Cytosol Plasma Membrane Synaptic Vesicle Dendritic Spine Synapse Perinuclear Region Of Cytoplasm Presynaptic Active Zone Membrane Schaffer Collateral - CA1 Synapse Glutamatergic Synapse	Plasma Membrane Cell-cell Junction Bicellular Tight Junction Basolateral Plasma Membrane Synapse MPP7-DLG1-LIN7 Complex Presynapse Postsynaptic Density Membrane
	Molecular Function	Amyloid-beta Binding Protein Binding	Protein Domain Specific Binding PDZ Domain Binding L27 Domain Binding
	Biological Process	In Utero Embryonic Development Intracellular Protein Transport Cell Adhesion Chemical Synaptic Transmission Neurotransmitter Secretion Nervous System Development Locomotory Behavior Axo-dendritic Transport Regulation Of Gene Expression Glutamate Secretion Gamma-aminobutyric Acid Secretion Multicellular Organism Growth Protein-containing Complex Assembly Regulation Of Synaptic Vesicle Exocytosis	Exocytosis Neurotransmitter Secretion Protein Transport Maintenance Of Epithelial Cell Apical/basal Polarity Protein Localization To Basolateral Plasma Membrane
Pathways		Dopamine Neurotransmitter Release Cycle Neurexins and neuroligins Assembly and cell surface presentation of NMDA receptors	Dopamine Neurotransmitter Release Cycle RHO GTPases Activate Rhotekin and Rhophilins Neurexins and neuroligins Assembly and cell surface presentation of NMDA receptors
Drugs
Diseases
GWAS		Cognitive ability ( 29186694) Cognitive ability (MTAG) ( 29186694) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Extremely high intelligence ( 29520040) Intelligence ( 28530673) Intelligence (MTAG) ( 29326435) Itch intensity from mosquito bite adjusted by bite size ( 28199695)
Interacting Genes		17 interacting genes: APP ARF3 ARF4 CACNA1B CASK CCS CNTNAP3 CNTNAP4 HTR2C KCNJ12 KIF17 LIN7B NOTCH1 NRXN1 PSEN1 STX1A STXBP1	11 interacting genes: ABCA1 APBA1 ASIC3 BAIAP2 CASK DLG4 GNG13 GRIK2 GRIN2B KCNJ12 KCNJ4
Entrez ID		320	64130
HPRD ID		03879	10040
Ensembl ID		ENSG00000107282	ENSG00000104863
Uniprot IDs		Q02410	Q9HAP6
PDB IDs		1AQC 1U37 1U38 1U39 1U3B 1X11 1X45 1Y7N	2DKR
Enriched GO Terms of Interacting Partners?
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