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FOXA2 and LHX1
Number of citations of the paper that reports this interaction (PubMedID
12642491
)
18
Data Source:
BioGRID
(pull down)
FOXA2
LHX1
Description
forkhead box A2
LIM homeobox 1
Image
No pdb structure
GO Annotations
Cellular Component
Nuclear Chromatin
Nucleus
Nucleoplasm
Cytoplasm
Cell Junction
Nuclear Chromatin
Nucleus
Transcription Factor Complex
Protein-containing Complex
Molecular Function
RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA Binding
DNA-binding Transcription Factor Activity
Transcription Factor Binding
Protein Domain Specific Binding
Transcription Regulatory Region DNA Binding
RNA Polymerase II Regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Proximal Promoter Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity
Transcription Corepressor Activity
Metal Ion Binding
Biological Process
Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose
Cell Fate Specification
Chromatin Organization
Regulation Of Transcription By RNA Polymerase II
Adult Locomotory Behavior
Anatomical Structure Morphogenesis
Negative Regulation Of Epithelial To Mesenchymal Transition
Cell Differentiation
Regulation Of Blood Coagulation
Endocrine Pancreas Development
Negative Regulation Of Glucokinase Activity
Positive Regulation Of Embryonic Development
Negative Regulation Of DNA-binding Transcription Factor Activity
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus
Negative Regulation Of Transcription From RNA Polymerase II Promoter By Glucose
Response To Interleukin-6
Dopaminergic Neuron Differentiation
Primitive Streak Formation
Positive Regulation Of Cell-cell Adhesion Mediated By Cadherin
Positive Regulation Of Gastrulation
Negative Regulation Of Detection Of Glucose
Urogenital System Development
Ureteric Bud Development
Branching Involved In Ureteric Bud Morphogenesis
Gastrulation With Mouth Forming Second
Ectoderm Formation
Endoderm Formation
Kidney Development
Transcription By RNA Polymerase II
Cell-cell Signaling
Pattern Specification Process
Nervous System Development
Motor Neuron Axon Guidance
Anatomical Structure Morphogenesis
Post-embryonic Development
Embryonic Pattern Specification
Animal Organ Morphogenesis
Anterior/posterior Axis Specification
Anterior/posterior Pattern Specification
Dorsal/ventral Pattern Formation
Regulation Of Gene Expression
Retina Layer Formation
Ventral Spinal Cord Development
Spinal Cord Association Neuron Differentiation
Telencephalon Development
Cerebellum Development
Cerebellar Purkinje Cell Differentiation
Forebrain Regionalization
Cerebellar Purkinje Cell-granule Cell Precursor Cell Signaling Involved In Regulation Of Granule Cell Precursor Cell Proliferation
Neuron Differentiation
Somite Rostral/caudal Axis Specification
Metanephric Part Of Ureteric Bud Development
Oviduct Epithelium Development
Uterine Epithelium Development
Nephric Duct Elongation
Horizontal Cell Localization
Positive Regulation Of Embryonic Development
Cellular Response To Fibroblast Growth Factor Stimulus
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Mesendoderm Development
Anatomical Structure Formation Involved In Morphogenesis
Embryonic Viscerocranium Morphogenesis
Pronephros Development
Embryonic Retina Morphogenesis In Camera-type Eye
Uterus Development
Oviduct Development
Cervix Development
Vagina Development
Head Development
Epithelium Development
Paramesonephric Duct Development
Comma-shaped Body Morphogenesis
S-shaped Body Morphogenesis
Renal Vesicle Morphogenesis
Mesonephric Duct Development
Nephric Duct Morphogenesis
Ureter Morphogenesis
Metanephric Glomerulus Development
Metanephric Comma-shaped Body Morphogenesis
Metanephric Renal Vesicle Morphogenesis
Metanephric S-shaped Body Morphogenesis
Primitive Streak Formation
Positive Regulation Of Branching Involved In Ureteric Bud Morphogenesis
Dorsal Spinal Cord Interneuron Posterior Axon Guidance
Lateral Motor Column Neuron Migration
Positive Regulation Of Gastrulation
Positive Regulation Of Anterior Head Development
Positive Regulation Of Nephron Tubule Epithelial Cell Differentiation
Pathways
Regulation of gene expression in beta cells
Drugs
Diseases
GWAS
Adolescent idiopathic scoliosis (
25784220
)
Birth weight (
31043758
)
Fasting blood glucose (
22581228
)
Fasting blood glucose (BMI interaction) (
22581228
)
Fasting plasma glucose (
25187374
20152958
)
Gout (
22179738
)
Hypothyroidism (
27182965
)
Male-pattern baldness (
22693459
27182965
)
Monobrow (
27182965
)
Type 2 diabetes (
30054458
)
Vitamin D levels (
26704534
)
Alzheimer's disease (
30636644
)
Body mass index (
26426971
)
HDL cholesterol x physical activity interaction (1df test) (
30670697
)
HDL cholesterol x physical activity interaction (2df test) (
30670697
)
Interacting Genes
9 interacting genes:
EN2
GSC
HOXA5
LHX1
MIP
NCOA1
ONECUT1
OTX2
TLE1
5 interacting genes:
FOXA2
ISL1
LHX3
OTX2
RLIM
Entrez ID
3170
3975
HPRD ID
02618
09067
Ensembl ID
ENSG00000125798
ENSG00000273706
Uniprot IDs
B0ZTD4
Q9Y261
P48742
Q58F18
PDB IDs
5X07
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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